PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15324899-1 2004 The introduction of 3-arylmethyl, 3-aryloxy and 3-arylthio moieties into a 6-methylsulfonylindole framework using rational drug design led to potent, selective COX-2 inhibitors having efficacy in a rat carrageenan air pouch model. Carrageenan 202-213 cytochrome c oxidase II, mitochondrial Rattus norvegicus 160-165