PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15313918-0	2004	A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.	sulforaphane	40-52	histone deacetylase 9	Homo sapiens	68-87	
15313918-3	2004	We tested the hypothesis that SFN acts as an inhibitor of histone deacetylase (HDAC).	sulforaphane	30-33	histone deacetylase 9	Homo sapiens	58-77	
15313918-3	2004	We tested the hypothesis that SFN acts as an inhibitor of histone deacetylase (HDAC).	sulforaphane	30-33	histone deacetylase 9	Homo sapiens	79-83	
15313918-8	2004	Finally, several of these findings were recapitulated in HCT116 human colorectal cancer cells: SFN dose-dependently increased TOPflash reporter activity and inhibited HDAC activity, there was an increase in acetylated histones and in p21(Cip1/Waf1), and chromatin immunoprecipitation assays revealed an increase in acetylated histones bound to the P21 promoter.	sulforaphane	95-98	histone deacetylase 9	Homo sapiens	167-171