PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15294346-4 2004 IL-1beta mRNA transcription was reduced by 35% following nitrite inhalant exposure, consistent with inhibition of activation-induced phosphorylation of macrophage mitogen-activated protein kinase p38. Nitrites 57-64 interleukin 1 beta Homo sapiens 0-8 15294346-7 2004 Nitrite inhalant exposure blocked activation-induced increases in caspase-1 activity, consistent with a 50% reduction in 17 kDa IL-1beta shown in Western blots. Nitrites 0-7 interleukin 1 beta Homo sapiens 128-136 15294346-8 2004 Thus, exposure to nitrite inhalants reduced macrophage production of IL-1beta by reducing transcription, as well as post-translational processing mediated by caspase-1. Nitrites 18-25 interleukin 1 beta Homo sapiens 69-77