PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15269007-0 2004 Decreased affinity for oxygen of cytochrome-c oxidase in Leigh syndrome caused by SURF1 mutations. Oxygen 23-29 cytochrome c oxidase subunit 8A Homo sapiens 33-53 15269007-4 2004 In both cases, the P50 in patients was elevated 2.1- and 3.3-fold, respectively, indicating decreased affinity of COX for oxygen. Oxygen 122-128 cytochrome c oxidase subunit 8A Homo sapiens 114-117