PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15255937-0	2004	The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK-ERK and Akt-independent mechanism.	5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone	20-26	mitogen-activated protein kinase kinase 7	Homo sapiens	115-118	
15255937-4	2004	In contrast to its effect in vitro, treatment of neurons with GW5074 causes c-Raf activation (when measured in vitro in the absence of the drug) and stimulates the Raf-MEK-ERK pathway.	5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone	62-68	mitogen-activated protein kinase kinase 7	Homo sapiens	168-171	
15255937-6	2004	PD98059 and U0126, two distinct inhibitors of MEK, block the activation of ERK by GW5074 but have no effect on its ability to prevent cell death.	5-iodo-3-((3,5-dibromo-4-hydroxyphenyl)methylene)-2-indolinone	82-88	mitogen-activated protein kinase kinase 7	Homo sapiens	46-49