PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15215482-0 2004 Treatment of skin papillomas with topical alpha-lactalbumin-oleic acid. Oleic Acid 60-70 lactalbumin alpha Homo sapiens 42-59 15215482-1 2004 BACKGROUND: We studied the effect on skin papillomas of topical application of a complex of alpha-lactalbumin and oleic acid (often referred to as human alpha-lactalbumin made lethal to tumor cells [HAMLET]) to establish proof of the principle that alpha-lactalbumin-oleic acid kills transformed cells but not healthy, differentiated cells. Oleic Acid 114-124 lactalbumin alpha Homo sapiens 153-170 15215482-1 2004 BACKGROUND: We studied the effect on skin papillomas of topical application of a complex of alpha-lactalbumin and oleic acid (often referred to as human alpha-lactalbumin made lethal to tumor cells [HAMLET]) to establish proof of the principle that alpha-lactalbumin-oleic acid kills transformed cells but not healthy, differentiated cells. Oleic Acid 114-124 lactalbumin alpha Homo sapiens 153-170 15215482-1 2004 BACKGROUND: We studied the effect on skin papillomas of topical application of a complex of alpha-lactalbumin and oleic acid (often referred to as human alpha-lactalbumin made lethal to tumor cells [HAMLET]) to establish proof of the principle that alpha-lactalbumin-oleic acid kills transformed cells but not healthy, differentiated cells. Oleic Acid 267-277 lactalbumin alpha Homo sapiens 92-109 15215482-1 2004 BACKGROUND: We studied the effect on skin papillomas of topical application of a complex of alpha-lactalbumin and oleic acid (often referred to as human alpha-lactalbumin made lethal to tumor cells [HAMLET]) to establish proof of the principle that alpha-lactalbumin-oleic acid kills transformed cells but not healthy, differentiated cells. Oleic Acid 267-277 lactalbumin alpha Homo sapiens 153-170 15215482-1 2004 BACKGROUND: We studied the effect on skin papillomas of topical application of a complex of alpha-lactalbumin and oleic acid (often referred to as human alpha-lactalbumin made lethal to tumor cells [HAMLET]) to establish proof of the principle that alpha-lactalbumin-oleic acid kills transformed cells but not healthy, differentiated cells. Oleic Acid 267-277 lactalbumin alpha Homo sapiens 153-170 15215482-2 2004 METHODS: Forty patients with cutaneous papillomas that were resistant to conventional treatment were enrolled in a randomized, placebo-controlled, double-blind study, in which alpha-lactalbumin-oleic acid or saline placebo was applied daily for three weeks and the change in the volume of each lesion was recorded. Oleic Acid 194-204 lactalbumin alpha Homo sapiens 176-193 15215482-5 2004 RESULTS: In the first phase of the study, the lesion volume was reduced by 75 percent or more in all 20 patients in the alpha-lactalbumin-oleic acid group, and in 88 of 92 papillomas; in the placebo group, a similar effect was evident in only 3 of 20 patients (15 of 74 papillomas) (P<0.001). Oleic Acid 138-148 lactalbumin alpha Homo sapiens 120-137