PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15067002-11 2004 Taken together, the present results indicate that the TPA-induced down-regulation of melanogenesis is mediated by PLD2 but not by PLD1 through the ubiquitin proteasome-mediated degradation of tyrosinase. Tetradecanoylphorbol Acetate 54-57 tyrosinase Mus musculus 192-202