PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15039766-6 2004 The interaction of D-amphetamine (D-amph) and the alpha2-AR-noradrenergic neuronal system in modulating startle reactivity and in regulating brain monoamine metabolism was assessed as the behavioral and neurochemical responses to D-amph alone, or to the combination of D-amph and dexmedetomidine or atipamezole. Dexmedetomidine 280-295 adrenergic receptor, alpha 2a Mus musculus 50-59 15039766-10 2004 alpha2A-AR also appeared to be responsible for the startle-modulating effects of alpha2-AR drugs, since the startle attenuation after the alpha2-AR agonist dexmedetomidine was absent in alpha2A-KO mice, and the alpha2-AR antagonist atipamezole had opposite effects on the startle reflex in alpha2A-KO and WT mice. Dexmedetomidine 156-171 adrenergic receptor, alpha 2a Mus musculus 0-10 15039766-10 2004 alpha2A-AR also appeared to be responsible for the startle-modulating effects of alpha2-AR drugs, since the startle attenuation after the alpha2-AR agonist dexmedetomidine was absent in alpha2A-KO mice, and the alpha2-AR antagonist atipamezole had opposite effects on the startle reflex in alpha2A-KO and WT mice. Dexmedetomidine 156-171 adrenergic receptor, alpha 2a Mus musculus 81-90