PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14980723-0 2004 Increased level of neuronal phosphoinositide 3-kinase gamma by the activation of mu-opioid receptor in the mouse periaqueductal gray matter: further evidence for the implication in morphine-induced antinociception. Morphine 181-189 opioid receptor, mu 1 Mus musculus 81-99 14980723-2 2004 The aim of the present study was to investigate whether in vivo treatment with morphine, a mu-opioid receptor (MOR) agonist, could directly regulate PI3Kgamma isoform in the mouse periaqueductal gray matter (PAG). Morphine 79-87 opioid receptor, mu 1 Mus musculus 91-109 14980723-2 2004 The aim of the present study was to investigate whether in vivo treatment with morphine, a mu-opioid receptor (MOR) agonist, could directly regulate PI3Kgamma isoform in the mouse periaqueductal gray matter (PAG). Morphine 79-87 opioid receptor, mu 1 Mus musculus 111-114 14980723-2 2004 The aim of the present study was to investigate whether in vivo treatment with morphine, a mu-opioid receptor (MOR) agonist, could directly regulate PI3Kgamma isoform in the mouse periaqueductal gray matter (PAG). Morphine 79-87 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Mus musculus 149-158 14980723-4 2004 A single s.c. injection of morphine caused a marked increase in the number of PI3Kgamma-IR expressing cells in the PAG. Morphine 27-35 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Mus musculus 78-87 14980723-10 2004 These findings suggested that acute treatment with morphine may directly activate the PI3Kgamma/PLCgamma1 pathway in the PAG. Morphine 51-59 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Mus musculus 86-95 14980723-10 2004 These findings suggested that acute treatment with morphine may directly activate the PI3Kgamma/PLCgamma1 pathway in the PAG. Morphine 51-59 phospholipase C, gamma 1 Mus musculus 96-105