PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14980205-1 2004 Activated protein C (APC), a serine protease with anticoagulant and anti-inflammatory activities, exerts direct cytoprotective effects on endothelium via endothelial protein C receptor-dependent activation of protease activated receptor 1 (PAR1). Serine 29-35 APC, WNT signaling pathway regulator Mus musculus 0-19 14980205-1 2004 Activated protein C (APC), a serine protease with anticoagulant and anti-inflammatory activities, exerts direct cytoprotective effects on endothelium via endothelial protein C receptor-dependent activation of protease activated receptor 1 (PAR1). Serine 29-35 APC, WNT signaling pathway regulator Mus musculus 21-24 14980205-2 2004 Here, we report that APC protects mouse cortical neurons from two divergent inducers of apoptosis, N-methyl-D-aspartate (NMDA) and staurosporine. N-Methylaspartate 99-119 APC, WNT signaling pathway regulator Mus musculus 21-24 14980205-2 2004 Here, we report that APC protects mouse cortical neurons from two divergent inducers of apoptosis, N-methyl-D-aspartate (NMDA) and staurosporine. N-Methylaspartate 121-125 APC, WNT signaling pathway regulator Mus musculus 21-24 14980205-2 2004 Here, we report that APC protects mouse cortical neurons from two divergent inducers of apoptosis, N-methyl-D-aspartate (NMDA) and staurosporine. Staurosporine 131-144 APC, WNT signaling pathway regulator Mus musculus 21-24 14980205-3 2004 APC blocked several steps in NMDA-induced apoptosis downstream to nitric oxide, i.e., caspase-3 activation, nuclear translocation of apoptosis-inducing factor (AIF), and induction of p53, and prevented staurosporine-induced apoptosis by blocking caspase-8 activation upstream of caspase-3 activation and AIF nuclear translocation. N-Methylaspartate 29-33 APC, WNT signaling pathway regulator Mus musculus 0-3 14980205-3 2004 APC blocked several steps in NMDA-induced apoptosis downstream to nitric oxide, i.e., caspase-3 activation, nuclear translocation of apoptosis-inducing factor (AIF), and induction of p53, and prevented staurosporine-induced apoptosis by blocking caspase-8 activation upstream of caspase-3 activation and AIF nuclear translocation. N-Methylaspartate 29-33 caspase 3 Mus musculus 86-95 14980205-3 2004 APC blocked several steps in NMDA-induced apoptosis downstream to nitric oxide, i.e., caspase-3 activation, nuclear translocation of apoptosis-inducing factor (AIF), and induction of p53, and prevented staurosporine-induced apoptosis by blocking caspase-8 activation upstream of caspase-3 activation and AIF nuclear translocation. N-Methylaspartate 29-33 apoptosis-inducing factor, mitochondrion-associated 1 Mus musculus 133-158 14980205-3 2004 APC blocked several steps in NMDA-induced apoptosis downstream to nitric oxide, i.e., caspase-3 activation, nuclear translocation of apoptosis-inducing factor (AIF), and induction of p53, and prevented staurosporine-induced apoptosis by blocking caspase-8 activation upstream of caspase-3 activation and AIF nuclear translocation. N-Methylaspartate 29-33 apoptosis-inducing factor, mitochondrion-associated 1 Mus musculus 160-163 14980205-3 2004 APC blocked several steps in NMDA-induced apoptosis downstream to nitric oxide, i.e., caspase-3 activation, nuclear translocation of apoptosis-inducing factor (AIF), and induction of p53, and prevented staurosporine-induced apoptosis by blocking caspase-8 activation upstream of caspase-3 activation and AIF nuclear translocation. N-Methylaspartate 29-33 transformation related protein 53, pseudogene Mus musculus 183-186 14980205-3 2004 APC blocked several steps in NMDA-induced apoptosis downstream to nitric oxide, i.e., caspase-3 activation, nuclear translocation of apoptosis-inducing factor (AIF), and induction of p53, and prevented staurosporine-induced apoptosis by blocking caspase-8 activation upstream of caspase-3 activation and AIF nuclear translocation. N-Methylaspartate 29-33 caspase 8 Mus musculus 246-255 14980205-3 2004 APC blocked several steps in NMDA-induced apoptosis downstream to nitric oxide, i.e., caspase-3 activation, nuclear translocation of apoptosis-inducing factor (AIF), and induction of p53, and prevented staurosporine-induced apoptosis by blocking caspase-8 activation upstream of caspase-3 activation and AIF nuclear translocation. N-Methylaspartate 29-33 caspase 3 Mus musculus 279-288 14980205-3 2004 APC blocked several steps in NMDA-induced apoptosis downstream to nitric oxide, i.e., caspase-3 activation, nuclear translocation of apoptosis-inducing factor (AIF), and induction of p53, and prevented staurosporine-induced apoptosis by blocking caspase-8 activation upstream of caspase-3 activation and AIF nuclear translocation. N-Methylaspartate 29-33 apoptosis-inducing factor, mitochondrion-associated 1 Mus musculus 304-307 14980205-3 2004 APC blocked several steps in NMDA-induced apoptosis downstream to nitric oxide, i.e., caspase-3 activation, nuclear translocation of apoptosis-inducing factor (AIF), and induction of p53, and prevented staurosporine-induced apoptosis by blocking caspase-8 activation upstream of caspase-3 activation and AIF nuclear translocation. Nitric Oxide 66-78 APC, WNT signaling pathway regulator Mus musculus 0-3 14980205-3 2004 APC blocked several steps in NMDA-induced apoptosis downstream to nitric oxide, i.e., caspase-3 activation, nuclear translocation of apoptosis-inducing factor (AIF), and induction of p53, and prevented staurosporine-induced apoptosis by blocking caspase-8 activation upstream of caspase-3 activation and AIF nuclear translocation. Staurosporine 202-215 APC, WNT signaling pathway regulator Mus musculus 0-3