PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14971644-0	2004	Arsenite induces HIF-1alpha and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells.	arsenite	0-8	AKT serine/threonine kinase 1	Homo sapiens	51-54	
14971644-7	2004	We also found that arsenite activates PI3K and Akt that are required for arsenite-induced expression of HIF-1alpha and VEGF.	arsenite	19-27	AKT serine/threonine kinase 1	Homo sapiens	47-50	
14971644-7	2004	We also found that arsenite activates PI3K and Akt that are required for arsenite-induced expression of HIF-1alpha and VEGF.	arsenite	73-81	AKT serine/threonine kinase 1	Homo sapiens	47-50	
14971644-11	2004	These data indicate that the arsenite-induced activation of PI3K/Akt signaling and the expression of HIF-1 and VEGF through the generation of ROS could be an important mechanism in the arsenite-induced carcinogenesis.	arsenite	29-37	AKT serine/threonine kinase 1	Homo sapiens	65-68	
14971644-11	2004	These data indicate that the arsenite-induced activation of PI3K/Akt signaling and the expression of HIF-1 and VEGF through the generation of ROS could be an important mechanism in the arsenite-induced carcinogenesis.	arsenite	185-193	AKT serine/threonine kinase 1	Homo sapiens	65-68