PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14757533-2 2004 Beginning with the observation that imatinib mesylate (Gleevec) could elicit rapid and complete hematologic remissions in a proportion of patients with HES, a reverse bedside-to-bench translational research effort led to the discovery of FIP1L1-PDGFRA, a novel fusion gene on chromosome 4q12 whose product is an imatinib-sensitive protein tyrosine kinase. Imatinib Mesylate 36-53 factor interacting with PAPOLA and CPSF1 Homo sapiens 238-244 14757533-2 2004 Beginning with the observation that imatinib mesylate (Gleevec) could elicit rapid and complete hematologic remissions in a proportion of patients with HES, a reverse bedside-to-bench translational research effort led to the discovery of FIP1L1-PDGFRA, a novel fusion gene on chromosome 4q12 whose product is an imatinib-sensitive protein tyrosine kinase. Imatinib Mesylate 36-44 factor interacting with PAPOLA and CPSF1 Homo sapiens 238-244