PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14737100-0 2004 Truncated ErbB2 receptor (p95ErbB2) is regulated by heregulin through heterodimer formation with ErbB3 yet remains sensitive to the dual EGFR/ErbB2 kinase inhibitor GW572016. Lapatinib 165-173 epidermal growth factor receptor Homo sapiens 137-141 14737100-5 2004 GW572016, a reversible small molecule inhibitor of EGFR and ErbB2 tyrosine kinases, inhibits baseline p95ErbB2 phosphorylation in BT474 cells and tumor xenografts. Lapatinib 0-8 epidermal growth factor receptor Homo sapiens 51-55 14737100-6 2004 Inhibition of p95ErbB2, p185ErbB2, and EGFR phosphorylation by GW572016 resulted in the inhibition of downstream phospho-Erk1/2, phospho-AKT, and cyclin D steady-state protein levels. Lapatinib 63-71 epidermal growth factor receptor Homo sapiens 39-43