PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14724828-3 2003 In 2 variations of the model an antisense oligonucleotide for nuclear factor kappa B (NF-kappa B) p65 was given prophylactically or therapeutically to block chronic inflammation-associated fibrosis. Oligonucleotides 42-57 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 62-84 14724828-3 2003 In 2 variations of the model an antisense oligonucleotide for nuclear factor kappa B (NF-kappa B) p65 was given prophylactically or therapeutically to block chronic inflammation-associated fibrosis. Oligonucleotides 42-57 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 86-96 14724828-3 2003 In 2 variations of the model an antisense oligonucleotide for nuclear factor kappa B (NF-kappa B) p65 was given prophylactically or therapeutically to block chronic inflammation-associated fibrosis. Oligonucleotides 42-57 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 98-101 14724828-8 2003 RESULTS: Colons of TNBS-treated mice contained acute and chronic inflammatory infiltrates, increased collagen, fibrogenic tissue architecture, and increased expression of TNF-alpha, TGF-beta 1, IGF-1, Col1a2, MMP-1, and TIMP-1. Trinitrobenzenesulfonic Acid 19-23 tumor necrosis factor Mus musculus 171-180 14724828-8 2003 RESULTS: Colons of TNBS-treated mice contained acute and chronic inflammatory infiltrates, increased collagen, fibrogenic tissue architecture, and increased expression of TNF-alpha, TGF-beta 1, IGF-1, Col1a2, MMP-1, and TIMP-1. Trinitrobenzenesulfonic Acid 19-23 transforming growth factor, beta 1 Mus musculus 182-192 14724828-8 2003 RESULTS: Colons of TNBS-treated mice contained acute and chronic inflammatory infiltrates, increased collagen, fibrogenic tissue architecture, and increased expression of TNF-alpha, TGF-beta 1, IGF-1, Col1a2, MMP-1, and TIMP-1. Trinitrobenzenesulfonic Acid 19-23 insulin-like growth factor 1 Mus musculus 194-199 14724828-8 2003 RESULTS: Colons of TNBS-treated mice contained acute and chronic inflammatory infiltrates, increased collagen, fibrogenic tissue architecture, and increased expression of TNF-alpha, TGF-beta 1, IGF-1, Col1a2, MMP-1, and TIMP-1. Trinitrobenzenesulfonic Acid 19-23 collagen, type I, alpha 2 Mus musculus 201-207 14724828-8 2003 RESULTS: Colons of TNBS-treated mice contained acute and chronic inflammatory infiltrates, increased collagen, fibrogenic tissue architecture, and increased expression of TNF-alpha, TGF-beta 1, IGF-1, Col1a2, MMP-1, and TIMP-1. Trinitrobenzenesulfonic Acid 19-23 matrix metallopeptidase 13 Mus musculus 209-214 14724828-8 2003 RESULTS: Colons of TNBS-treated mice contained acute and chronic inflammatory infiltrates, increased collagen, fibrogenic tissue architecture, and increased expression of TNF-alpha, TGF-beta 1, IGF-1, Col1a2, MMP-1, and TIMP-1. Trinitrobenzenesulfonic Acid 19-23 tissue inhibitor of metalloproteinase 1 Mus musculus 220-226 14724828-9 2003 Colonic mesenchymal cells from TNBS-treated mice were also morphologically distinct from those of the control mice, with increased TIMP-1 expression in response to IFN-gamma treatment. Trinitrobenzenesulfonic Acid 31-35 tissue inhibitor of metalloproteinase 1 Mus musculus 131-137 14724828-9 2003 Colonic mesenchymal cells from TNBS-treated mice were also morphologically distinct from those of the control mice, with increased TIMP-1 expression in response to IFN-gamma treatment. Trinitrobenzenesulfonic Acid 31-35 interferon gamma Mus musculus 164-173 14724828-12 2003 CONCLUSIONS: Extended TNBS treatment of mice yielded chronic intestinal inflammation-associated fibrosis with extensive fibrogenic ECM changes that could be counteracted by specific blockade of NF-kappa B. Trinitrobenzenesulfonic Acid 22-26 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 194-204