PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14662774-0 2004 Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1. Troglitazone 78-90 growth differentiation factor 15 Homo sapiens 14-19 14662774-0 2004 Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1. Troglitazone 78-90 early growth response 1 Homo sapiens 131-136 14662774-1 2004 Troglitazone (TGZ) and 15-deoxy-Delta(12,14)-prostaglandin J2 (PGJ2) are peroxisome proliferator-activated receptor-gamma (PPARgamma) ligands that have been shown to possess pro-apoptotic activity in human colon cancer. Troglitazone 0-12 peroxisome proliferator activated receptor gamma Homo sapiens 73-121 14662774-1 2004 Troglitazone (TGZ) and 15-deoxy-Delta(12,14)-prostaglandin J2 (PGJ2) are peroxisome proliferator-activated receptor-gamma (PPARgamma) ligands that have been shown to possess pro-apoptotic activity in human colon cancer. Troglitazone 0-12 peroxisome proliferator activated receptor gamma Homo sapiens 123-132 14662774-1 2004 Troglitazone (TGZ) and 15-deoxy-Delta(12,14)-prostaglandin J2 (PGJ2) are peroxisome proliferator-activated receptor-gamma (PPARgamma) ligands that have been shown to possess pro-apoptotic activity in human colon cancer. Troglitazone 14-17 peroxisome proliferator activated receptor gamma Homo sapiens 73-121 14662774-1 2004 Troglitazone (TGZ) and 15-deoxy-Delta(12,14)-prostaglandin J2 (PGJ2) are peroxisome proliferator-activated receptor-gamma (PPARgamma) ligands that have been shown to possess pro-apoptotic activity in human colon cancer. Troglitazone 14-17 peroxisome proliferator activated receptor gamma Homo sapiens 123-132 14662774-1 2004 Troglitazone (TGZ) and 15-deoxy-Delta(12,14)-prostaglandin J2 (PGJ2) are peroxisome proliferator-activated receptor-gamma (PPARgamma) ligands that have been shown to possess pro-apoptotic activity in human colon cancer. 15-deoxy-delta(12,14)-prostaglandin J2 23-61 peroxisome proliferator activated receptor gamma Homo sapiens 73-121 14662774-1 2004 Troglitazone (TGZ) and 15-deoxy-Delta(12,14)-prostaglandin J2 (PGJ2) are peroxisome proliferator-activated receptor-gamma (PPARgamma) ligands that have been shown to possess pro-apoptotic activity in human colon cancer. 15-deoxy-delta(12,14)-prostaglandin J2 23-61 peroxisome proliferator activated receptor gamma Homo sapiens 123-132 14662774-1 2004 Troglitazone (TGZ) and 15-deoxy-Delta(12,14)-prostaglandin J2 (PGJ2) are peroxisome proliferator-activated receptor-gamma (PPARgamma) ligands that have been shown to possess pro-apoptotic activity in human colon cancer. 15-deoxy-delta(12,14)-prostaglandin J2 63-67 peroxisome proliferator activated receptor gamma Homo sapiens 73-121 14662774-1 2004 Troglitazone (TGZ) and 15-deoxy-Delta(12,14)-prostaglandin J2 (PGJ2) are peroxisome proliferator-activated receptor-gamma (PPARgamma) ligands that have been shown to possess pro-apoptotic activity in human colon cancer. 15-deoxy-delta(12,14)-prostaglandin J2 63-67 peroxisome proliferator activated receptor gamma Homo sapiens 123-132 14662774-3 2004 We previously reported that TGZ induces an early growth response transcription factor (EGR-1) by the ERK phosphorylation pathway rather than by the PPARgamma pathway (Baek, S. J., Wilson, L. C., Hsi, L. C., and Eling, T. E. (2003) J. Biol. Troglitazone 28-31 early growth response 1 Homo sapiens 87-92 14662774-6 2004 In this report, we show that the expression of the antitumorigenic and/or pro-apoptotic gene NAG-1 (nonsteroidal anti-inflammatory drug-activated gene-1) is induced by TGZ and correlates with EGR-1 induction. Troglitazone 168-171 growth differentiation factor 15 Homo sapiens 93-98 14662774-6 2004 In this report, we show that the expression of the antitumorigenic and/or pro-apoptotic gene NAG-1 (nonsteroidal anti-inflammatory drug-activated gene-1) is induced by TGZ and correlates with EGR-1 induction. Troglitazone 168-171 growth differentiation factor 15 Homo sapiens 100-152 14662774-6 2004 In this report, we show that the expression of the antitumorigenic and/or pro-apoptotic gene NAG-1 (nonsteroidal anti-inflammatory drug-activated gene-1) is induced by TGZ and correlates with EGR-1 induction. Troglitazone 168-171 early growth response 1 Homo sapiens 192-197 14662774-8 2004 In contrast, PGJ2 induced NAG-1 protein expression, but PGJ2 may not affect the same region that TGZ does in the NAG-1 promoter. 15-deoxy-delta(12,14)-prostaglandin J2 13-17 growth differentiation factor 15 Homo sapiens 26-31 14662774-9 2004 The effect of PGJ2 is probably PPARgamma-dependent because a PPARgamma antagonist inhibited the PGJ2-induced expression of NAG-1. 15-deoxy-delta(12,14)-prostaglandin J2 14-18 peroxisome proliferator activated receptor gamma Homo sapiens 31-40 14662774-9 2004 The effect of PGJ2 is probably PPARgamma-dependent because a PPARgamma antagonist inhibited the PGJ2-induced expression of NAG-1. 15-deoxy-delta(12,14)-prostaglandin J2 14-18 peroxisome proliferator activated receptor gamma Homo sapiens 61-70 14662774-9 2004 The effect of PGJ2 is probably PPARgamma-dependent because a PPARgamma antagonist inhibited the PGJ2-induced expression of NAG-1. 15-deoxy-delta(12,14)-prostaglandin J2 14-18 growth differentiation factor 15 Homo sapiens 123-128 14662774-9 2004 The effect of PGJ2 is probably PPARgamma-dependent because a PPARgamma antagonist inhibited the PGJ2-induced expression of NAG-1. 15-deoxy-delta(12,14)-prostaglandin J2 96-100 peroxisome proliferator activated receptor gamma Homo sapiens 31-40 14662774-9 2004 The effect of PGJ2 is probably PPARgamma-dependent because a PPARgamma antagonist inhibited the PGJ2-induced expression of NAG-1. 15-deoxy-delta(12,14)-prostaglandin J2 96-100 peroxisome proliferator activated receptor gamma Homo sapiens 61-70 14662774-9 2004 The effect of PGJ2 is probably PPARgamma-dependent because a PPARgamma antagonist inhibited the PGJ2-induced expression of NAG-1. 15-deoxy-delta(12,14)-prostaglandin J2 96-100 growth differentiation factor 15 Homo sapiens 123-128 14662774-10 2004 TGZ-induced NAG-1 expression was not inhibited by the PPARgamma antagonist. Troglitazone 0-3 growth differentiation factor 15 Homo sapiens 12-17