PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14623899-1	2004	Ser/Thr phosphorylation of insulin receptor substrate IRS-1 regulates insulin signaling, but the relevant phosphorylated residues and their potential functions during insulin-stimulated signal transduction are difficult to resolve.	Serine	0-3	insulin receptor substrate 1	Mus musculus	54-59	
14623899-1	2004	Ser/Thr phosphorylation of insulin receptor substrate IRS-1 regulates insulin signaling, but the relevant phosphorylated residues and their potential functions during insulin-stimulated signal transduction are difficult to resolve.	Threonine	4-7	insulin receptor substrate 1	Mus musculus	54-59	
14623899-3	2004	Insulin or IGF-I stimulated phosphorylation of Ser(302) in various cell backgrounds and in murine muscle.	Serine	47-50	insulin-like growth factor 1	Mus musculus	11-16	
14623899-4	2004	Wortmannin or rapamycin inhibited Ser(302) phosphorylation, and amino acids or glucose stimulated Ser(302) phosphorylation, suggesting a role for the mTOR cascade.	Wortmannin	0-10	mechanistic target of rapamycin kinase	Mus musculus	150-154	
14623899-4	2004	Wortmannin or rapamycin inhibited Ser(302) phosphorylation, and amino acids or glucose stimulated Ser(302) phosphorylation, suggesting a role for the mTOR cascade.	Glucose	79-86	mechanistic target of rapamycin kinase	Mus musculus	150-154	
14623899-4	2004	Wortmannin or rapamycin inhibited Ser(302) phosphorylation, and amino acids or glucose stimulated Ser(302) phosphorylation, suggesting a role for the mTOR cascade.	Serine	98-101	mechanistic target of rapamycin kinase	Mus musculus	150-154	
14623899-7	2004	Replacing Ser(302) with alanine significantly reduced insulin-stimulated tyrosine phosphorylation of IRS-1 and p85 binding and reduced insulin-stimulated phosphorylation of p70(S6K), ribosomal S6 protein, and 4E-BP1; however, this mutation had no effect on insulin-stimulated Akt or glycogen synthase kinase 3beta phosphorylation.	Tyrosine	73-81	insulin receptor substrate 1	Mus musculus	101-106	
14623899-9	2004	We conclude that Ser(302) phosphorylation integrates nutrient availability with insulin/IGF-I signaling to promote mitogenesis and cell growth.	Serine	17-20	insulin-like growth factor 1	Mus musculus	88-93