PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14622092-2 2003 Nicotine-induced neuroprotection against different toxins is imparted through pharmacologically distinct neuronal nicotinic acetylcholine receptors (nAChR) where protection against chronic N-methyl-d-aspartic acid (NMDA) exposure is through nAChRalpha7 but protection against the toxic peptide of amyloid precursor protein, Abeta25-35, is through nAChRalpha4beta2. Nicotine 0-8 cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus 114-147 14622092-2 2003 Nicotine-induced neuroprotection against different toxins is imparted through pharmacologically distinct neuronal nicotinic acetylcholine receptors (nAChR) where protection against chronic N-methyl-d-aspartic acid (NMDA) exposure is through nAChRalpha7 but protection against the toxic peptide of amyloid precursor protein, Abeta25-35, is through nAChRalpha4beta2. Nicotine 0-8 cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus 149-154 14622092-7 2003 Therefore, the neuroprotective effects of nicotine against differing toxic assaults requires distinct nAChR subtypes and proceeds through intracellular pathways that overlap with similarly different mechanisms initiated by pro-inflammatory cytokines. Nicotine 42-50 cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus 102-107