PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14592853-2 2004 We examined the potential possibility of an interaction between nicotine, a major component of cigarette smoke, and angiotensin II (Ang II), which plays an important role in the pathogenesis of cardiovascular diseases characterized by Ang II type 1 (AT1) receptor-mediated abnormal growth of vascular smooth muscle cells (VSMC) and fibroblasts. Nicotine 64-72 angiotensin II receptor, type 1a Rattus norvegicus 250-253