PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14580160-3 2003 Normal prolidase II was very labile in the absence of MnCl2 or mercaptoethanol. manganese chloride 54-59 peptidase D Homo sapiens 7-16 14580160-4 2003 The activity of prolidase II was maintained at about 76% by pre-incubation with MnCl2; it was then activated up to 140% by treatment with mercaptoethanol for 60 minutes at 37 degrees C. Normal prolidases I and II showed the highest activity against glycylproline or methionylproline in the presence of MnCl2. manganese chloride 80-85 peptidase D Homo sapiens 16-25 14580160-4 2003 The activity of prolidase II was maintained at about 76% by pre-incubation with MnCl2; it was then activated up to 140% by treatment with mercaptoethanol for 60 minutes at 37 degrees C. Normal prolidases I and II showed the highest activity against glycylproline or methionylproline in the presence of MnCl2. manganese chloride 302-307 peptidase D Homo sapiens 16-25 14580160-5 2003 The activity of prolidase I against glycylproline was enhanced strongly by glycine and MnCl2, but not activated in the absence of MnCl2. manganese chloride 87-92 peptidase D Homo sapiens 16-25 14580160-6 2003 The activity of prolidase II against methionylproline was enhanced three-fold in the presence of glycine and MnCl2, but its activity against glycylproline was very low even in the presence of MnCl2. manganese chloride 109-114 peptidase D Homo sapiens 16-25 14580160-6 2003 The activity of prolidase II against methionylproline was enhanced three-fold in the presence of glycine and MnCl2, but its activity against glycylproline was very low even in the presence of MnCl2. manganese chloride 192-197 peptidase D Homo sapiens 16-25 14580160-8 2003 The activity of prolidase II against methionylproline in all erythrocytes, of normal humans and of patients, was strongly activated by the addition of glycine with MnCl2 but suppressed by the addition of mercaptoethanol. manganese chloride 164-169 peptidase D Homo sapiens 16-25