PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14555937-10 2003 CONCLUSION: We conclude that Rac1 is required in ROS generation and NF-kappaB activation after hepatic I/R in vivo, and that inactivation of NF-kappaB in NPCs and suppression of ROS generation in NPCs and hepatocytes possibly account for the protective effect of N17Rac1 in this study. Reactive Oxygen Species 49-52 Rac family small GTPase 1 Rattus norvegicus 29-33