PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1445297-0	1992	Cell killing and induction of manganous superoxide dismutase by tumor necrosis factor-alpha is mediated by lipoxygenase metabolites of arachidonic acid.	Arachidonic Acid	135-151	tumor necrosis factor	Homo sapiens	64-91	
1445297-2	1992	A role for lipoxygenase metabolites of arachidonic acid as mediators of TNF action in the induction of c-fos has been described.	Arachidonic Acid	39-55	tumor necrosis factor	Homo sapiens	72-75	
1445297-2	1992	A role for lipoxygenase metabolites of arachidonic acid as mediators of TNF action in the induction of c-fos has been described.	Arachidonic Acid	39-55	Fos proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	103-108	
1445297-3	1992	In this paper we report that acute cytotoxicity elicited by TNF, in the presence of cycloheximide (CHX), also utilizes this pathway since inhibitors of lipoxygenase action fully prevent TNF/CHX killing of several cell lines.	Cycloheximide	84-97	tumor necrosis factor	Homo sapiens	60-63	
1445297-3	1992	In this paper we report that acute cytotoxicity elicited by TNF, in the presence of cycloheximide (CHX), also utilizes this pathway since inhibitors of lipoxygenase action fully prevent TNF/CHX killing of several cell lines.	Cycloheximide	84-97	tumor necrosis factor	Homo sapiens	186-189	
1445297-3	1992	In this paper we report that acute cytotoxicity elicited by TNF, in the presence of cycloheximide (CHX), also utilizes this pathway since inhibitors of lipoxygenase action fully prevent TNF/CHX killing of several cell lines.	Cycloheximide	99-102	tumor necrosis factor	Homo sapiens	60-63	
1445297-3	1992	In this paper we report that acute cytotoxicity elicited by TNF, in the presence of cycloheximide (CHX), also utilizes this pathway since inhibitors of lipoxygenase action fully prevent TNF/CHX killing of several cell lines.	Cycloheximide	99-102	tumor necrosis factor	Homo sapiens	186-189	
1445297-5	1992	Radical scavengers such as NAC and PDTC prevent TNF/CHX-induced cell killing and reduce MnSOD induction by TNF.	Cycloheximide	52-55	synuclein alpha	Homo sapiens	27-30	
1445297-5	1992	Radical scavengers such as NAC and PDTC prevent TNF/CHX-induced cell killing and reduce MnSOD induction by TNF.	Cycloheximide	52-55	tumor necrosis factor	Homo sapiens	48-51	
1445297-6	1992	Therefore, cell death by TNF/CHX treatment occurs via a pathway in which lipoxygenase products directly or indirectly operate via the generation of superoxide anions.	Superoxides	148-165	tumor necrosis factor	Homo sapiens	25-28