PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1445251-2 1992 The effect of the cyclic-AMP/CRP complex on the linear P4 promoter was to increase the initial binding (KB) of RNA polymerase to the promoter by about a factor of 10, but the rate of isomerization of closed to open complex (kf) was unaffected. Cyclic AMP 18-28 catabolite gene activator protein Escherichia coli 29-32 1445251-3 1992 One molecule of CRP per promoter was required for activation, and the concentration of cyclic AMP producing half-maximal stimulation was about 7-8 microM. Cyclic AMP 87-97 catabolite gene activator protein Escherichia coli 16-19