PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1369587-3 1992 In this report, microinjection of 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT), a selective 5-HT1A agonist, into the PVN increased rat plasma ACTH concentration in a dose-related manner. 8-Hydroxy-2-(di-n-propylamino)tetralin 34-73 5-hydroxytryptamine receptor 1A Rattus norvegicus 99-105 1369587-3 1992 In this report, microinjection of 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT), a selective 5-HT1A agonist, into the PVN increased rat plasma ACTH concentration in a dose-related manner. 8-Hydroxy-2-(di-n-propylamino)tetralin 75-84 5-hydroxytryptamine receptor 1A Rattus norvegicus 99-105 1369587-4 1992 Similar responses were observed when two other 5-HT1A agonists, busipirone and gepirone, were used. busipirone 64-74 5-hydroxytryptamine receptor 1A Rattus norvegicus 47-53 1369587-5 1992 (+/-)-Pindolol, known to have 5-HT1A antagonist properties, blocked the effect induced by an optimal dose of 8-OH-DPAT after injection into the PVN. Pindolol 0-14 5-hydroxytryptamine receptor 1A Rattus norvegicus 30-36 1369587-5 1992 (+/-)-Pindolol, known to have 5-HT1A antagonist properties, blocked the effect induced by an optimal dose of 8-OH-DPAT after injection into the PVN. 8-Hydroxy-2-(di-n-propylamino)tetralin 109-118 5-hydroxytryptamine receptor 1A Rattus norvegicus 30-36 1369587-6 1992 This same dose of 8-OH-DPAT also induced a decrease of hypothalamic CRH concentration, which was completely antagonized as well by pretreatment injection of (+/-)-pindolol into the PVN. 8-Hydroxy-2-(di-n-propylamino)tetralin 18-27 corticotropin releasing hormone Rattus norvegicus 68-71 1369587-6 1992 This same dose of 8-OH-DPAT also induced a decrease of hypothalamic CRH concentration, which was completely antagonized as well by pretreatment injection of (+/-)-pindolol into the PVN. Pindolol 157-171 corticotropin releasing hormone Rattus norvegicus 68-71