PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
13679060-1	2003	Recent studies from our laboratory demonstrated that Egr-1 is upregulated in the rat duodenal mucosa during cysteamine-induced duodenal ulceration and that antisense egr-1 oligonucleotide aggravates the duodenal ulcers.	Cysteamine	108-118	early growth response 1	Rattus norvegicus	53-58	
13679060-1	2003	Recent studies from our laboratory demonstrated that Egr-1 is upregulated in the rat duodenal mucosa during cysteamine-induced duodenal ulceration and that antisense egr-1 oligonucleotide aggravates the duodenal ulcers.	Cysteamine	108-118	early growth response 1	Rattus norvegicus	166-171	
13679060-2	2003	This study was aimed to determine the effects of cysteamine on redox-sensitive Egr-1 transcriptional activity and on other thiol-containing proteins such as redox factor-1 (Ref-1) and thioredoxin (Trx).	Cysteamine	49-59	early growth response 1	Rattus norvegicus	79-84	
13679060-3	2003	Here we demonstrate for the first time that cysteamine increases the expression and nuclear translocation of Egr-1, Ref-1, and Trx, and activates binding of Egr-1 to DNA.	Cysteamine	44-54	early growth response 1	Rattus norvegicus	109-114	
13679060-3	2003	Here we demonstrate for the first time that cysteamine increases the expression and nuclear translocation of Egr-1, Ref-1, and Trx, and activates binding of Egr-1 to DNA.	Cysteamine	44-54	early growth response 1	Rattus norvegicus	157-162	
13679060-4	2003	Moreover, we also show that Egr-1 forms a complex with other redox-sensitive transcription factors (e.g., AP-1, AP-2, NFATc, Sp1, PAX-5, MTF-1, c-Myb, and CREB) in rat duodenal mucosa and that cysteamine enhances the formation of these complexes.	Cysteamine	193-203	early growth response 1	Rattus norvegicus	28-33