PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1360981-2 1992 P-gp has been localized to the apical plasma membrane of the bile canaliculus where it has been shown to transport [3H]daunomycin. Daunorubicin 119-129 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 0-4 1360981-3 1992 In this study, we investigated whether alterations in membrane lipid fluidity of canalicular membrane vesicles (CMV) could modulate the P-gp-mediated accumulation of [3H]daunomycin and [3H]vinblastine. Daunorubicin 170-180 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 136-140 1360981-11 1992 Verapamil competitively inhibited P-gp-mediated accumulation of [3H]daunomycin but failed to alter the fluidity of CMV. Daunorubicin 68-78 ATP-binding cassette, subfamily B (MDR/TAP), member 1B Rattus norvegicus 34-38