PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1359961-1	1992	We have investigated the direct effects of different neuroexcitatory amino acids (EAA) on the secretion of CRH-41 and arginine vasopressin (AVP) from the rat hypothalamus maintained in vitro.	Excitatory Amino Acids	82-85	corticotropin releasing hormone	Rattus norvegicus	107-110	
1359961-1	1992	We have investigated the direct effects of different neuroexcitatory amino acids (EAA) on the secretion of CRH-41 and arginine vasopressin (AVP) from the rat hypothalamus maintained in vitro.	Excitatory Amino Acids	82-85	arginine vasopressin	Rattus norvegicus	127-138	
1359961-4	1992	Finally, we investigated whether different periods of exposure (up to 100 min) of hypothalamic explants to NMDA and KA would affect CRH-41 release.	N-Methylaspartate	107-111	corticotropin releasing hormone	Rattus norvegicus	132-135	
1359961-5	1992	While no EAA was able to induce CRH-41 release under any of the above conditions, 20-min incubations with NMDA in the dose range of 1 nM to 1 mM in the absence of added Mg2+ significantly stimulated AVP release in a dose-related fashion; the maximum effect occurred at a concentration of 1 mM [ratio of stimulated collection/basal collection: NMDA, 1.51 +/- 0.10, controls, 0.86 +/- 0.05 (mean +/- SEM); P < 0.001].	N-Methylaspartate	106-110	corticotropin releasing hormone	Rattus norvegicus	32-35