PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1359141-2	1992	These imidazo[1,2-a]pyrazines were evaluated for their binding affinity to the alpha 1, alpha 2, beta 1, and beta 2 adrenergic receptors as well as their ability to lower blood glucose in insulin resistant hyperglycemic ob/ob mice.	imidazo(1,2-a)pyrazine	6-29	hemoglobin, beta adult major chain	Mus musculus	79-115	
1359141-3	1992	Modifications on 8-(1-piperazinyl)imidazo[1,2-a]pyrazine (4) reduced alpha 2 binding, lowered hypoglycemic potency, and showed variations in binding to the alpha 1, beta 1, and beta 2 adrenergic receptors.	8-(1-piperazinyl)imidazo(1,2-a)pyrazine	17-56	hemoglobin, beta adult major chain	Mus musculus	165-171	
1359141-3	1992	Modifications on 8-(1-piperazinyl)imidazo[1,2-a]pyrazine (4) reduced alpha 2 binding, lowered hypoglycemic potency, and showed variations in binding to the alpha 1, beta 1, and beta 2 adrenergic receptors.	8-(1-piperazinyl)imidazo(1,2-a)pyrazine	17-56	hemoglobin, beta adult minor chain	Mus musculus	177-183	
1359141-5	1992	Receptor binding was modified by use of a 4-methylpiperazine moiety which reduced alpha 1 and beta 1 binding while retaining some hypoglycemic activity.	1-methylpiperazine	42-60	hemoglobin, beta adult major chain	Mus musculus	94-100