PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1311561-0	1992	Investigation of guanine-nucleotide-binding protein involvement and regulation of cyclic AMP metabolism in interleukin 1 signal transduction.	Guanine Nucleotides	17-35	interleukin 1 complex	Mus musculus	107-120	
1311561-0	1992	Investigation of guanine-nucleotide-binding protein involvement and regulation of cyclic AMP metabolism in interleukin 1 signal transduction.	Cyclic AMP	82-92	interleukin 1 complex	Mus musculus	107-120	
1311561-1	1992	The involvement of guanine-nucleotide-binding proteins (G-proteins) and regulation of cyclic AMP (cAMP) in interleukin 1 (IL1) signal transduction has been investigated in EL4 and 7OZ/3 cells expressing Type 1 and Type 2 IL1 receptors respectively.	Cyclic AMP	98-102	interleukin 1 complex	Mus musculus	107-120	
1311561-5	1992	In EL4-cell membrane preparations the kinetics of 125I-IL1 binding were altered in the presence of guanosine 5"-[beta gamma-imido]triphosphate, resulting in the formation of a higher-affinity state for IL1 binding.	Guanylyl Imidodiphosphate	99-142	interleukin 1 complex	Mus musculus	55-58	
1311561-5	1992	In EL4-cell membrane preparations the kinetics of 125I-IL1 binding were altered in the presence of guanosine 5"-[beta gamma-imido]triphosphate, resulting in the formation of a higher-affinity state for IL1 binding.	Guanylyl Imidodiphosphate	99-142	interleukin 1 complex	Mus musculus	202-205	
1311561-7	1992	These results suggest that IL1 receptor function may be regulated by guanine nucleotides; however, the mechanism appears to differ from that exhibited by conventional G-protein-linked receptors.	Guanine Nucleotides	69-88	interleukin 1 complex	Mus musculus	27-30