PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12963487-0	2003	Genistein reduces NF-kappa B in T lymphoma cells via a caspase-mediated cleavage of I kappa B alpha.	Genistein	0-9	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	18-28	
12963487-0	2003	Genistein reduces NF-kappa B in T lymphoma cells via a caspase-mediated cleavage of I kappa B alpha.	Genistein	0-9	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	84-99	
12963487-2	2003	When T lymphoma cells were treated with the soy isoflavone genistein, a marked reduction in nuclear NF-kappa B levels was detectable predominantly for the p50/p50 homodimer and p50/p65 heterodimer.	Isoflavones	48-58	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	100-110	
12963487-2	2003	When T lymphoma cells were treated with the soy isoflavone genistein, a marked reduction in nuclear NF-kappa B levels was detectable predominantly for the p50/p50 homodimer and p50/p65 heterodimer.	Isoflavones	48-58	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	155-158	
12963487-2	2003	When T lymphoma cells were treated with the soy isoflavone genistein, a marked reduction in nuclear NF-kappa B levels was detectable predominantly for the p50/p50 homodimer and p50/p65 heterodimer.	Isoflavones	48-58	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	159-162	
12963487-2	2003	When T lymphoma cells were treated with the soy isoflavone genistein, a marked reduction in nuclear NF-kappa B levels was detectable predominantly for the p50/p50 homodimer and p50/p65 heterodimer.	Isoflavones	48-58	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	159-162	
12963487-2	2003	When T lymphoma cells were treated with the soy isoflavone genistein, a marked reduction in nuclear NF-kappa B levels was detectable predominantly for the p50/p50 homodimer and p50/p65 heterodimer.	Isoflavones	48-58	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mus musculus	181-184	
12963487-2	2003	When T lymphoma cells were treated with the soy isoflavone genistein, a marked reduction in nuclear NF-kappa B levels was detectable predominantly for the p50/p50 homodimer and p50/p65 heterodimer.	Genistein	59-68	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	100-110	
12963487-2	2003	When T lymphoma cells were treated with the soy isoflavone genistein, a marked reduction in nuclear NF-kappa B levels was detectable predominantly for the p50/p50 homodimer and p50/p65 heterodimer.	Genistein	59-68	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	155-158	
12963487-2	2003	When T lymphoma cells were treated with the soy isoflavone genistein, a marked reduction in nuclear NF-kappa B levels was detectable predominantly for the p50/p50 homodimer and p50/p65 heterodimer.	Genistein	59-68	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	159-162	
12963487-2	2003	When T lymphoma cells were treated with the soy isoflavone genistein, a marked reduction in nuclear NF-kappa B levels was detectable predominantly for the p50/p50 homodimer and p50/p65 heterodimer.	Genistein	59-68	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	159-162	
12963487-2	2003	When T lymphoma cells were treated with the soy isoflavone genistein, a marked reduction in nuclear NF-kappa B levels was detectable predominantly for the p50/p50 homodimer and p50/p65 heterodimer.	Genistein	59-68	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mus musculus	181-184	
12963487-3	2003	To examine the mechanism by which NF-kappa B is reduced by genistein, we analyzed the NF-kappa B inhibitor, I kappa B alpha, and detected a 34 kDa cleavage product Delta I kappa B alpha, which was induced by genistein in a dose-dependent manner.	Genistein	59-68	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	34-44	
12963487-3	2003	To examine the mechanism by which NF-kappa B is reduced by genistein, we analyzed the NF-kappa B inhibitor, I kappa B alpha, and detected a 34 kDa cleavage product Delta I kappa B alpha, which was induced by genistein in a dose-dependent manner.	Genistein	59-68	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta	Mus musculus	86-106	
12963487-3	2003	To examine the mechanism by which NF-kappa B is reduced by genistein, we analyzed the NF-kappa B inhibitor, I kappa B alpha, and detected a 34 kDa cleavage product Delta I kappa B alpha, which was induced by genistein in a dose-dependent manner.	Genistein	59-68	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	108-123	
12963487-3	2003	To examine the mechanism by which NF-kappa B is reduced by genistein, we analyzed the NF-kappa B inhibitor, I kappa B alpha, and detected a 34 kDa cleavage product Delta I kappa B alpha, which was induced by genistein in a dose-dependent manner.	Genistein	59-68	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	170-185	
12963487-3	2003	To examine the mechanism by which NF-kappa B is reduced by genistein, we analyzed the NF-kappa B inhibitor, I kappa B alpha, and detected a 34 kDa cleavage product Delta I kappa B alpha, which was induced by genistein in a dose-dependent manner.	Genistein	208-217	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	34-44	
12963487-3	2003	To examine the mechanism by which NF-kappa B is reduced by genistein, we analyzed the NF-kappa B inhibitor, I kappa B alpha, and detected a 34 kDa cleavage product Delta I kappa B alpha, which was induced by genistein in a dose-dependent manner.	Genistein	208-217	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta	Mus musculus	86-106	
12963487-3	2003	To examine the mechanism by which NF-kappa B is reduced by genistein, we analyzed the NF-kappa B inhibitor, I kappa B alpha, and detected a 34 kDa cleavage product Delta I kappa B alpha, which was induced by genistein in a dose-dependent manner.	Genistein	208-217	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	108-123	
12963487-3	2003	To examine the mechanism by which NF-kappa B is reduced by genistein, we analyzed the NF-kappa B inhibitor, I kappa B alpha, and detected a 34 kDa cleavage product Delta I kappa B alpha, which was induced by genistein in a dose-dependent manner.	Genistein	208-217	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	170-185	
12963487-4	2003	Our observation that a pan-caspase inhibitor could inhibit the induction of Delta I kappa B alpha by genistein suggested that caspase activity was responsible for this cleavage product.	Genistein	101-110	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	82-97	
12963487-5	2003	In support of this idea, we detected an increase in caspase-3 activity in response to increasing time of genistein exposure.	Genistein	105-114	caspase 3	Mus musculus	52-61	
12963487-7	2003	These results support a direct role for Delta I kappa B alpha in the reduction of NF-kappa B by genistein.	Genistein	96-105	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	46-61	
12963487-7	2003	These results support a direct role for Delta I kappa B alpha in the reduction of NF-kappa B by genistein.	Genistein	96-105	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	82-92	
12963487-9	2003	Only changes in A1 and cIAP-1 levels were affected with significant reductions in response to genistein.	Genistein	94-103	baculoviral IAP repeat-containing 3	Mus musculus	23-29	
12963487-10	2003	Generation of the repressive activity of Delta I kappa B alpha on NF-kappa B is a novel mechanism for the reduction of this transcription factor by genistein and the possible effect this may have on the ability of genistein to induce apoptosis in tumor cells.	Genistein	148-157	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	47-62	
12963487-10	2003	Generation of the repressive activity of Delta I kappa B alpha on NF-kappa B is a novel mechanism for the reduction of this transcription factor by genistein and the possible effect this may have on the ability of genistein to induce apoptosis in tumor cells.	Genistein	148-157	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	66-76	
12963487-10	2003	Generation of the repressive activity of Delta I kappa B alpha on NF-kappa B is a novel mechanism for the reduction of this transcription factor by genistein and the possible effect this may have on the ability of genistein to induce apoptosis in tumor cells.	Genistein	214-223	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	47-62	
12963487-10	2003	Generation of the repressive activity of Delta I kappa B alpha on NF-kappa B is a novel mechanism for the reduction of this transcription factor by genistein and the possible effect this may have on the ability of genistein to induce apoptosis in tumor cells.	Genistein	214-223	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	66-76