PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12952926-4 2003 In the presence of concentrations of CTLA-4Ig that inhibited the CD28-B7 interaction, beryllium-specific CD4+ T cells in lung were still able to proliferate and secrete IFN-gamma in response to beryllium in culture. Beryllium 86-95 CD28 molecule Homo sapiens 65-69 12952926-4 2003 In the presence of concentrations of CTLA-4Ig that inhibited the CD28-B7 interaction, beryllium-specific CD4+ T cells in lung were still able to proliferate and secrete IFN-gamma in response to beryllium in culture. Beryllium 194-203 CD28 molecule Homo sapiens 65-69 12952926-6 2003 Although lung CD4+CD28- cells retained the ability to secrete Th1-type cytokines in response to beryllium, they showed less proliferative capacity and were more susceptible to cell death compared with CD28+ T cells. Beryllium 96-105 CD28 molecule Homo sapiens 18-22 12952926-7 2003 In contrast to lung cells, inhibition of the CD28-B7 interaction markedly reduced responses of beryllium-specific T cells in blood. Beryllium 95-104 CD28 molecule Homo sapiens 45-49