PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12913062-1	2003	The present study evaluated the potential mechanism involved in the hypotensive effect induced by ET-1 in rats treated with the NO synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME) in the drinking water during 7 days.	NG-Nitroarginine Methyl Ester	150-182	endothelin 1	Rattus norvegicus	98-102	
12913062-1	2003	The present study evaluated the potential mechanism involved in the hypotensive effect induced by ET-1 in rats treated with the NO synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME) in the drinking water during 7 days.	NG-Nitroarginine Methyl Ester	184-190	endothelin 1	Rattus norvegicus	98-102	
12913062-3	2003	The enhanced ET-1 hypotensive effect in L-NAME-treated rats was abolished by the ETB receptor antagonist BQ-788 but was unaltered by the cyclooxygenase inhibitor diclofenac, the cytochrome P450 inhibitor fluconazole, or the potassium channel blockers apamin, glibenclamide, tetraethylammonium, and 4-aminopyridine.	NG-Nitroarginine Methyl Ester	40-46	endothelin 1	Rattus norvegicus	13-17	
12913062-4	2003	Pretreatment with the cannabinoid CB1 receptor antagonist SR141716A significantly reduced the hypotensive response to ET-1 in L-NAME-treated rats (20+/-1%), although it did not modify the response in untreated control rats (17+/-1%).	NG-Nitroarginine Methyl Ester	126-132	endothelin 1	Rattus norvegicus	118-122