PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12909725-7 2003 We demonstrate that our error-prone Pol I can be used to generate enzymes with distinct properties by generating TEM-1 beta-lactamase mutants able to hydrolyze a third-generation lactam antibiotic, aztreonam. Aztreonam 198-207 TEM-1 beta-lactamase Escherichia coli 113-133