PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12867541-0 2003 Distribution and trafficking of MPR300 is normal in cells with cholesterol accumulated in late endocytic compartments: evidence for early endosome-to-TGN trafficking of MPR300. Cholesterol 63-74 insulin like growth factor 2 receptor Homo sapiens 32-38 12867541-1 2003 It has been reported that an accumulation of cholesterol within late endosomes/lysosomes in Niemann-Pick type C (NPC) fibroblasts and U18666A-treated cells causes impairment of retrograde trafficking of the cation-independent mannose 6-phosphate/IGF-II receptor (MPR300) from late endosomes to the trans-Golgi network (TGN). Cholesterol 45-56 NPC intracellular cholesterol transporter 1 Homo sapiens 92-111 12867541-1 2003 It has been reported that an accumulation of cholesterol within late endosomes/lysosomes in Niemann-Pick type C (NPC) fibroblasts and U18666A-treated cells causes impairment of retrograde trafficking of the cation-independent mannose 6-phosphate/IGF-II receptor (MPR300) from late endosomes to the trans-Golgi network (TGN). Cholesterol 45-56 NPC intracellular cholesterol transporter 1 Homo sapiens 113-116 12867541-1 2003 It has been reported that an accumulation of cholesterol within late endosomes/lysosomes in Niemann-Pick type C (NPC) fibroblasts and U18666A-treated cells causes impairment of retrograde trafficking of the cation-independent mannose 6-phosphate/IGF-II receptor (MPR300) from late endosomes to the trans-Golgi network (TGN). Cholesterol 45-56 insulin like growth factor 2 receptor Homo sapiens 246-261 12867541-1 2003 It has been reported that an accumulation of cholesterol within late endosomes/lysosomes in Niemann-Pick type C (NPC) fibroblasts and U18666A-treated cells causes impairment of retrograde trafficking of the cation-independent mannose 6-phosphate/IGF-II receptor (MPR300) from late endosomes to the trans-Golgi network (TGN). Cholesterol 45-56 insulin like growth factor 2 receptor Homo sapiens 263-269 12867541-1 2003 It has been reported that an accumulation of cholesterol within late endosomes/lysosomes in Niemann-Pick type C (NPC) fibroblasts and U18666A-treated cells causes impairment of retrograde trafficking of the cation-independent mannose 6-phosphate/IGF-II receptor (MPR300) from late endosomes to the trans-Golgi network (TGN). mannose-6-phosphate 226-245 NPC intracellular cholesterol transporter 1 Homo sapiens 92-111 12867541-1 2003 It has been reported that an accumulation of cholesterol within late endosomes/lysosomes in Niemann-Pick type C (NPC) fibroblasts and U18666A-treated cells causes impairment of retrograde trafficking of the cation-independent mannose 6-phosphate/IGF-II receptor (MPR300) from late endosomes to the trans-Golgi network (TGN). mannose-6-phosphate 226-245 NPC intracellular cholesterol transporter 1 Homo sapiens 113-116 12867541-5 2003 Furthermore, treatment of normal and NPC fibroblasts with chloroquine, which inhibits membrane traffic from early endosomes to the TGN, resulted in a redistribution of MPR300 to EEA1 and internalized transferrin-positive, but LAMP-2-negative, early-recycling endosomes. Chloroquine 58-69 NPC intracellular cholesterol transporter 1 Homo sapiens 37-40 12867541-5 2003 Furthermore, treatment of normal and NPC fibroblasts with chloroquine, which inhibits membrane traffic from early endosomes to the TGN, resulted in a redistribution of MPR300 to EEA1 and internalized transferrin-positive, but LAMP-2-negative, early-recycling endosomes. Chloroquine 58-69 insulin like growth factor 2 receptor Homo sapiens 168-174 12867541-5 2003 Furthermore, treatment of normal and NPC fibroblasts with chloroquine, which inhibits membrane traffic from early endosomes to the TGN, resulted in a redistribution of MPR300 to EEA1 and internalized transferrin-positive, but LAMP-2-negative, early-recycling endosomes. Chloroquine 58-69 early endosome antigen 1 Homo sapiens 178-182 12867541-5 2003 Furthermore, treatment of normal and NPC fibroblasts with chloroquine, which inhibits membrane traffic from early endosomes to the TGN, resulted in a redistribution of MPR300 to EEA1 and internalized transferrin-positive, but LAMP-2-negative, early-recycling endosomes. Chloroquine 58-69 transferrin Homo sapiens 200-211 12867541-5 2003 Furthermore, treatment of normal and NPC fibroblasts with chloroquine, which inhibits membrane traffic from early endosomes to the TGN, resulted in a redistribution of MPR300 to EEA1 and internalized transferrin-positive, but LAMP-2-negative, early-recycling endosomes. Chloroquine 58-69 lysosomal associated membrane protein 2 Homo sapiens 226-232