PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1284994-0 1992 Pivotal role of hepatocellular regeneration in the ultimate hepatotoxicity of CCl4 in chlordecone-, mirex-, or phenobarbital-pretreated rats. Chlordecone 86-97 C-C motif chemokine ligand 4 Rattus norvegicus 78-82 1284994-1 1992 Our earlier histomorphometric and biochemical studies suggested that the progressive phase of the interactive toxicity of chlordecone (CD) + CCl4 involves suppression of hepatocellular regeneration. Chlordecone 122-133 C-C motif chemokine ligand 4 Rattus norvegicus 141-145 1284994-6 1992 Dietary 10 ppm CD potentiated the hepatotoxicity of CCl4 to a greater extent than PB or M, as evidenced by elevations in plasma enzymes. Chlordecone 15-17 C-C motif chemokine ligand 4 Rattus norvegicus 52-56 1284994-9 1992 Actual liver injury by CCl4 was greater in PB- than in CD-pretreated rats, as evidenced by histopathological observations. Chlordecone 55-57 C-C motif chemokine ligand 4 Rattus norvegicus 23-27 1284994-10 1992 A 100% mortality occurred in CD-pretreated rats at 60 hr after CCl4 administration, whereas no mortality occurred in either N-, M-, or PB-pretreated rats, indicating recovery from liver injury. Chlordecone 29-31 C-C motif chemokine ligand 4 Rattus norvegicus 63-67 1284994-11 1992 Hepatocellular nuclear DNA levels were significantly decreased starting at 6 hr after CCl4 administration to CD-pretreated rats, but not in M- or PB-pretreated rats. Chlordecone 109-111 C-C motif chemokine ligand 4 Rattus norvegicus 86-90