PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12824177-4 2003 Exposure of bovine aortic endothelial cells (BAEC) to chemically synthesized ONOO- acutely and significantly increased phosphorylation of c-Src, PDK1, AMPK, and its downstream target, acetyl-CoA carboxylase (ACC), without affecting cellular AMP. onoo 77-81 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 151-155 12824177-8 2003 Moreover, H/R, like ONOO-, significantly increased co-immunoprecipitation of AMPK with c-Src, suggesting that ONOO- favors physical association of AMPK with upstream kinases. onoo 20-24 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 77-81 12824177-8 2003 Moreover, H/R, like ONOO-, significantly increased co-immunoprecipitation of AMPK with c-Src, suggesting that ONOO- favors physical association of AMPK with upstream kinases. onoo 20-24 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 147-151 12824177-8 2003 Moreover, H/R, like ONOO-, significantly increased co-immunoprecipitation of AMPK with c-Src, suggesting that ONOO- favors physical association of AMPK with upstream kinases. onoo 110-114 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 77-81 12824177-8 2003 Moreover, H/R, like ONOO-, significantly increased co-immunoprecipitation of AMPK with c-Src, suggesting that ONOO- favors physical association of AMPK with upstream kinases. onoo 110-114 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 147-151 12824177-9 2003 Taken together, our results indicate a novel pathway by which H/R via ONOO- activates AMPK in a c-Src-mediated, PI 3-kinase-dependent manner, and suggest that ONOO--induced activation of AMPK might thereby regulate metabolic enzymes, such as ACC. onoo 70-74 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 86-90 12824177-9 2003 Taken together, our results indicate a novel pathway by which H/R via ONOO- activates AMPK in a c-Src-mediated, PI 3-kinase-dependent manner, and suggest that ONOO--induced activation of AMPK might thereby regulate metabolic enzymes, such as ACC. onoo 70-74 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 187-191 12824177-9 2003 Taken together, our results indicate a novel pathway by which H/R via ONOO- activates AMPK in a c-Src-mediated, PI 3-kinase-dependent manner, and suggest that ONOO--induced activation of AMPK might thereby regulate metabolic enzymes, such as ACC. onoo 159-163 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 86-90 12824177-9 2003 Taken together, our results indicate a novel pathway by which H/R via ONOO- activates AMPK in a c-Src-mediated, PI 3-kinase-dependent manner, and suggest that ONOO--induced activation of AMPK might thereby regulate metabolic enzymes, such as ACC. onoo 159-163 protein kinase AMP-activated catalytic subunit alpha 1 Homo sapiens 187-191