PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12723971-3 2003 L-Buthionine-( S, R )-sulphoximine, which decreases intracellular glutathione content, enhanced glucose deprivation-induced activation of JNK1 by promoting the dissociation of TRX, but not GRX, from ASK1. l-buthionine-( s, r )-sulphoximine 0-34 mitogen-activated protein kinase 8 Homo sapiens 138-142 12723971-3 2003 L-Buthionine-( S, R )-sulphoximine, which decreases intracellular glutathione content, enhanced glucose deprivation-induced activation of JNK1 by promoting the dissociation of TRX, but not GRX, from ASK1. l-buthionine-( s, r )-sulphoximine 0-34 thioredoxin Homo sapiens 176-179 12723971-3 2003 L-Buthionine-( S, R )-sulphoximine, which decreases intracellular glutathione content, enhanced glucose deprivation-induced activation of JNK1 by promoting the dissociation of TRX, but not GRX, from ASK1. l-buthionine-( s, r )-sulphoximine 0-34 glutaredoxin Homo sapiens 189-192 12723971-3 2003 L-Buthionine-( S, R )-sulphoximine, which decreases intracellular glutathione content, enhanced glucose deprivation-induced activation of JNK1 by promoting the dissociation of TRX, but not GRX, from ASK1. l-buthionine-( s, r )-sulphoximine 0-34 mitogen-activated protein kinase kinase kinase 5 Homo sapiens 199-203 12723971-3 2003 L-Buthionine-( S, R )-sulphoximine, which decreases intracellular glutathione content, enhanced glucose deprivation-induced activation of JNK1 by promoting the dissociation of TRX, but not GRX, from ASK1. Glucose 96-103 mitogen-activated protein kinase 8 Homo sapiens 138-142 12723971-3 2003 L-Buthionine-( S, R )-sulphoximine, which decreases intracellular glutathione content, enhanced glucose deprivation-induced activation of JNK1 by promoting the dissociation of TRX, but not GRX, from ASK1. Glucose 96-103 thioredoxin Homo sapiens 176-179 12723971-3 2003 L-Buthionine-( S, R )-sulphoximine, which decreases intracellular glutathione content, enhanced glucose deprivation-induced activation of JNK1 by promoting the dissociation of TRX, but not GRX, from ASK1. Glucose 96-103 glutaredoxin Homo sapiens 189-192 12723971-3 2003 L-Buthionine-( S, R )-sulphoximine, which decreases intracellular glutathione content, enhanced glucose deprivation-induced activation of JNK1 by promoting the dissociation of TRX, but not GRX, from ASK1. Glucose 96-103 mitogen-activated protein kinase kinase kinase 5 Homo sapiens 199-203 12723971-4 2003 Treatment of cells with exogenous glutathione disulphide ester resulted in the dissociation of GRX, but not TRX, from ASK1 and the subsequent activation of JNK1. glutathione disulphide ester 34-62 glutaredoxin Homo sapiens 95-98 12723971-4 2003 Treatment of cells with exogenous glutathione disulphide ester resulted in the dissociation of GRX, but not TRX, from ASK1 and the subsequent activation of JNK1. glutathione disulphide ester 34-62 thioredoxin Homo sapiens 108-111 12723971-4 2003 Treatment of cells with exogenous glutathione disulphide ester resulted in the dissociation of GRX, but not TRX, from ASK1 and the subsequent activation of JNK1. glutathione disulphide ester 34-62 mitogen-activated protein kinase kinase kinase 5 Homo sapiens 118-122 12723971-4 2003 Treatment of cells with exogenous glutathione disulphide ester resulted in the dissociation of GRX, but not TRX, from ASK1 and the subsequent activation of JNK1. glutathione disulphide ester 34-62 mitogen-activated protein kinase 8 Homo sapiens 156-160 12723971-6 2003 Taken together, glucose deprivation-induced metabolic oxidative stress may activate ASK1 through two different pathways: glutathione-dependent GRX-ASK1 and glutathione-independent TRX-ASK1 pathways. Glucose 16-23 mitogen-activated protein kinase kinase kinase 5 Homo sapiens 84-88 12723971-6 2003 Taken together, glucose deprivation-induced metabolic oxidative stress may activate ASK1 through two different pathways: glutathione-dependent GRX-ASK1 and glutathione-independent TRX-ASK1 pathways. Glucose 16-23 glutaredoxin Homo sapiens 143-151 12723971-6 2003 Taken together, glucose deprivation-induced metabolic oxidative stress may activate ASK1 through two different pathways: glutathione-dependent GRX-ASK1 and glutathione-independent TRX-ASK1 pathways. Glucose 16-23 thioredoxin Homo sapiens 180-188 12723971-6 2003 Taken together, glucose deprivation-induced metabolic oxidative stress may activate ASK1 through two different pathways: glutathione-dependent GRX-ASK1 and glutathione-independent TRX-ASK1 pathways. Glutathione 121-132 mitogen-activated protein kinase kinase kinase 5 Homo sapiens 84-88 12723971-6 2003 Taken together, glucose deprivation-induced metabolic oxidative stress may activate ASK1 through two different pathways: glutathione-dependent GRX-ASK1 and glutathione-independent TRX-ASK1 pathways. Glutathione 121-132 glutaredoxin Homo sapiens 143-151 12723971-6 2003 Taken together, glucose deprivation-induced metabolic oxidative stress may activate ASK1 through two different pathways: glutathione-dependent GRX-ASK1 and glutathione-independent TRX-ASK1 pathways. Glutathione 156-167 mitogen-activated protein kinase kinase kinase 5 Homo sapiens 84-88