PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12720581-4 2003 In a macrophage cell line (RAW 264.7) activated with interferon gamma plus lipopolysaccharide, both isoflavones were found to inhibit NO production and tumour necrosis factor alpha (TNF-alpha) secretion dose-dependently, but they did not affect mRNA levels for inducible nitric oxide synthase and cyclo-oxygenase-2. Isoflavones 100-111 tumor necrosis factor Homo sapiens 182-191 12720581-5 2003 Both isoflavones also dose-dependently decreased monocyte chemoattractant protein-1 secretion induced by TNF-alpha in human umbilical vein endothelial cells. Isoflavones 5-16 tumor necrosis factor Homo sapiens 105-114