PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12646577-2	2003	We have previously reported that prostaglandin F2 alpha (PGF2 alpha) activates p44/p42 mitogen-activated protein kinase (MAPK) through protein kinase C (PKC) in osteoblast-like MC3T3-E1 cells.	Dinoprost	33-49	mitogen-activated protein kinase 3	Mus musculus	79-82	
12646577-2	2003	We have previously reported that prostaglandin F2 alpha (PGF2 alpha) activates p44/p42 mitogen-activated protein kinase (MAPK) through protein kinase C (PKC) in osteoblast-like MC3T3-E1 cells.	Dinoprost	57-61	mitogen-activated protein kinase 3	Mus musculus	79-82	
12646577-17	2003	Incadronate markedly enhanced the phosphorylation of Raf-1, MEK1/2, and p44/p42 MAPK induced by PGF2 alpha or 12-O-tetradecanoylphorbol-13-acetate, a PKC activator.	Dinoprost	96-106	mitogen-activated protein kinase 3	Mus musculus	72-75	
12646577-19	2003	These results strongly suggest that PGF2 alpha stimulates VEGF synthesis through the PKC-dependent activation of p44/p42 MAPK in osteoblasts and that the incadronate enhances the VEGF synthesis at the point between PKC and Raf-1.	Dinoprost	36-40	mitogen-activated protein kinase 3	Mus musculus	113-116