PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12617904-3 2003 The X-ray structure of the complex of topiramate with hCA II has been solved and it revealed a very tight association of the inhibitor, with a network of seven strong hydrogen bonds fixing topiramate within the active site, in addition to the Zn(II) coordination through the ionized sulfamate moiety. Zinc 243-249 carbonic anhydrase 2 Homo sapiens 54-60