PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12509295-2 2002 Though Mre11p has both single-stranded and double-stranded 3"-5" exonuclease activity in vitro, null mutants of MRE11, RAD50, and XRS2 exhibit reduced 5"-3" resection of HO-induced double-strand breaks (DSBs) in vivo. dsbs 203-207 Xrs2p Saccharomyces cerevisiae S288C 130-134