PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12471138-0 2002 Hydrogen peroxide induces murine macrophage chemokine gene transcription via extracellular signal-regulated kinase- and cyclic adenosine 5"-monophosphate (cAMP)-dependent pathways: involvement of NF-kappa B, activator protein 1, and cAMP response element binding protein. Hydrogen Peroxide 0-17 mitogen-activated protein kinase 1 Mus musculus 77-114 12471138-0 2002 Hydrogen peroxide induces murine macrophage chemokine gene transcription via extracellular signal-regulated kinase- and cyclic adenosine 5"-monophosphate (cAMP)-dependent pathways: involvement of NF-kappa B, activator protein 1, and cAMP response element binding protein. Hydrogen Peroxide 0-17 cathelicidin antimicrobial peptide Mus musculus 120-153 12471138-0 2002 Hydrogen peroxide induces murine macrophage chemokine gene transcription via extracellular signal-regulated kinase- and cyclic adenosine 5"-monophosphate (cAMP)-dependent pathways: involvement of NF-kappa B, activator protein 1, and cAMP response element binding protein. Hydrogen Peroxide 0-17 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 196-227 12471138-0 2002 Hydrogen peroxide induces murine macrophage chemokine gene transcription via extracellular signal-regulated kinase- and cyclic adenosine 5"-monophosphate (cAMP)-dependent pathways: involvement of NF-kappa B, activator protein 1, and cAMP response element binding protein. Cyclic AMP 155-159 cathelicidin antimicrobial peptide Mus musculus 120-153 12471138-4 2002 Blockage of the ERK pathway with specific inhibitors against mitogen-activated protein kinase kinase 1/2 and ERK1/ERK2 completely abolished both the H(2)O(2)-mediated chemokine up-regulation and the activation of all NF studied. Hydrogen Peroxide 149-157 mitogen-activated protein kinase 1 Mus musculus 16-19 12471138-4 2002 Blockage of the ERK pathway with specific inhibitors against mitogen-activated protein kinase kinase 1/2 and ERK1/ERK2 completely abolished both the H(2)O(2)-mediated chemokine up-regulation and the activation of all NF studied. Hydrogen Peroxide 149-157 mitogen-activated protein kinase kinase 1 Mus musculus 61-104 12471138-4 2002 Blockage of the ERK pathway with specific inhibitors against mitogen-activated protein kinase kinase 1/2 and ERK1/ERK2 completely abolished both the H(2)O(2)-mediated chemokine up-regulation and the activation of all NF studied. Hydrogen Peroxide 149-157 mitogen-activated protein kinase 3 Mus musculus 109-113 12471138-4 2002 Blockage of the ERK pathway with specific inhibitors against mitogen-activated protein kinase kinase 1/2 and ERK1/ERK2 completely abolished both the H(2)O(2)-mediated chemokine up-regulation and the activation of all NF studied. Hydrogen Peroxide 149-157 mitogen-activated protein kinase 1 Mus musculus 114-118 12471138-5 2002 Similarly, selective inhibition of cAMP and NF-kappaB strongly down-regulated the induction of all chemokine transcripts as well as CREB and NF-kappaB activation, respectively. Cyclic AMP 35-39 cAMP responsive element binding protein 1 Mus musculus 132-136 12471138-6 2002 Of interest, we detected a significant decrease of NF-kappaB, AP-1, and CREB DNA binding activities by reciprocal competition for these binding sites when either specific cold oligonucleotides (NF-kappaB, AP-1, and CREB) or Abs against various transcription factor subunits (p50, p65, c-Fos, Jun B, c-Jun, and CREB-1) were added. Oligonucleotides 176-192 cAMP responsive element binding protein 1 Mus musculus 72-76 12471138-6 2002 Of interest, we detected a significant decrease of NF-kappaB, AP-1, and CREB DNA binding activities by reciprocal competition for these binding sites when either specific cold oligonucleotides (NF-kappaB, AP-1, and CREB) or Abs against various transcription factor subunits (p50, p65, c-Fos, Jun B, c-Jun, and CREB-1) were added. Oligonucleotides 176-192 cAMP responsive element binding protein 1 Mus musculus 215-219 12471138-6 2002 Of interest, we detected a significant decrease of NF-kappaB, AP-1, and CREB DNA binding activities by reciprocal competition for these binding sites when either specific cold oligonucleotides (NF-kappaB, AP-1, and CREB) or Abs against various transcription factor subunits (p50, p65, c-Fos, Jun B, c-Jun, and CREB-1) were added. Oligonucleotides 176-192 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 275-278 12471138-6 2002 Of interest, we detected a significant decrease of NF-kappaB, AP-1, and CREB DNA binding activities by reciprocal competition for these binding sites when either specific cold oligonucleotides (NF-kappaB, AP-1, and CREB) or Abs against various transcription factor subunits (p50, p65, c-Fos, Jun B, c-Jun, and CREB-1) were added. Oligonucleotides 176-192 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 280-283 12471138-6 2002 Of interest, we detected a significant decrease of NF-kappaB, AP-1, and CREB DNA binding activities by reciprocal competition for these binding sites when either specific cold oligonucleotides (NF-kappaB, AP-1, and CREB) or Abs against various transcription factor subunits (p50, p65, c-Fos, Jun B, c-Jun, and CREB-1) were added. Oligonucleotides 176-192 FBJ osteosarcoma oncogene Mus musculus 285-290 12471138-6 2002 Of interest, we detected a significant decrease of NF-kappaB, AP-1, and CREB DNA binding activities by reciprocal competition for these binding sites when either specific cold oligonucleotides (NF-kappaB, AP-1, and CREB) or Abs against various transcription factor subunits (p50, p65, c-Fos, Jun B, c-Jun, and CREB-1) were added. Oligonucleotides 176-192 jun B proto-oncogene Mus musculus 292-297 12471138-6 2002 Of interest, we detected a significant decrease of NF-kappaB, AP-1, and CREB DNA binding activities by reciprocal competition for these binding sites when either specific cold oligonucleotides (NF-kappaB, AP-1, and CREB) or Abs against various transcription factor subunits (p50, p65, c-Fos, Jun B, c-Jun, and CREB-1) were added. Oligonucleotides 176-192 jun proto-oncogene Mus musculus 299-304 12471138-6 2002 Of interest, we detected a significant decrease of NF-kappaB, AP-1, and CREB DNA binding activities by reciprocal competition for these binding sites when either specific cold oligonucleotides (NF-kappaB, AP-1, and CREB) or Abs against various transcription factor subunits (p50, p65, c-Fos, Jun B, c-Jun, and CREB-1) were added. Oligonucleotides 176-192 cAMP responsive element binding protein 1 Mus musculus 310-316 12471138-8 2002 Finally, experiments performed with actinomycin D suggest that H(2)O(2)-mediated MIP-1beta mRNA up-regulation results from transcriptional control, whereas that of MIP-1alpha, MIP-2, and monocyte chemoattractant protein-1 is due to both gene transcription activation and mRNA posttranscriptional stabilization. Dactinomycin 36-49 chemokine (C-C motif) ligand 4 Mus musculus 81-90 12471138-8 2002 Finally, experiments performed with actinomycin D suggest that H(2)O(2)-mediated MIP-1beta mRNA up-regulation results from transcriptional control, whereas that of MIP-1alpha, MIP-2, and monocyte chemoattractant protein-1 is due to both gene transcription activation and mRNA posttranscriptional stabilization. Hydrogen Peroxide 63-71 chemokine (C-C motif) ligand 4 Mus musculus 81-90