PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12424743-0	2002	Differential stimulation of IgE production, STAT activation and cytokine and CD86 expression by 2,4-dinitrochlorobenzene and trimellitic anhydride.	Dinitrochlorobenzene	96-120	CD86 antigen	Mus musculus	77-81	
12424743-0	2002	Differential stimulation of IgE production, STAT activation and cytokine and CD86 expression by 2,4-dinitrochlorobenzene and trimellitic anhydride.	trimellitic anhydride	125-146	CD86 antigen	Mus musculus	77-81	
12424743-1	2002	It has been reported that dermal exposure to trimellitic anhydride (TMA, 50%), a respiratory allergen, induced greater production of serum IgE and expression of Th2 cytokines than 2,4-dinitrochlorobenzene (DNCB, 1%), a potent contact sensitizer, in female BALB/C mice.	trimellitic anhydride	68-71	heart and neural crest derivatives expressed 2	Mus musculus	161-164	
12424743-4	2002	In vitro expression of interleukin 4 (IL-4) and IL-13 mRNA by overnight concanavalin A (ConA)-stimulated draining lymph node cells was enhanced following in vivo treatment with TMA but not with DNCB in the B6C3F1, C57BL/6 and BDF1 mice.	trimellitic anhydride	177-180	interleukin 4	Mus musculus	23-36	
12424743-4	2002	In vitro expression of interleukin 4 (IL-4) and IL-13 mRNA by overnight concanavalin A (ConA)-stimulated draining lymph node cells was enhanced following in vivo treatment with TMA but not with DNCB in the B6C3F1, C57BL/6 and BDF1 mice.	trimellitic anhydride	177-180	interleukin 4	Mus musculus	38-42	
12424743-4	2002	In vitro expression of interleukin 4 (IL-4) and IL-13 mRNA by overnight concanavalin A (ConA)-stimulated draining lymph node cells was enhanced following in vivo treatment with TMA but not with DNCB in the B6C3F1, C57BL/6 and BDF1 mice.	trimellitic anhydride	177-180	interleukin 13	Mus musculus	48-53	
12424743-5	2002	In contrast, TMA and DNCB induced similar levels of IL-4 and IL-13 mRNA in the BALB/C mice.	trimellitic anhydride	13-16	interleukin 4	Mus musculus	52-56	
12424743-5	2002	In contrast, TMA and DNCB induced similar levels of IL-4 and IL-13 mRNA in the BALB/C mice.	trimellitic anhydride	13-16	interleukin 13	Mus musculus	61-66	
12424743-5	2002	In contrast, TMA and DNCB induced similar levels of IL-4 and IL-13 mRNA in the BALB/C mice.	Dinitrochlorobenzene	21-25	interleukin 4	Mus musculus	52-56	
12424743-5	2002	In contrast, TMA and DNCB induced similar levels of IL-4 and IL-13 mRNA in the BALB/C mice.	Dinitrochlorobenzene	21-25	interleukin 13	Mus musculus	61-66	
12424743-6	2002	The IL-4 protein levels in the supernatants of overnight ConA-treated draining lymph node cells were also increased in TMA-treated B6C3F1 and C57BL/6 mice when compared with the DNCB treatment and vehicle controls.	trimellitic anhydride	119-122	interleukin 4	Mus musculus	4-8	
12424743-6	2002	The IL-4 protein levels in the supernatants of overnight ConA-treated draining lymph node cells were also increased in TMA-treated B6C3F1 and C57BL/6 mice when compared with the DNCB treatment and vehicle controls.	Dinitrochlorobenzene	178-182	interleukin 4	Mus musculus	4-8	
12424743-7	2002	Further mechanistic evaluation in the B6C3F1 mice indicated that the activation of STAT6 but not STAT4 by ConA plus IL-2-treated draining lymph node cells was increased in TMA- but not DNCB-treated mice when compared with the vehicle controls.	trimellitic anhydride	172-175	signal transducer and activator of transcription 6	Mus musculus	83-88	
12424743-7	2002	Further mechanistic evaluation in the B6C3F1 mice indicated that the activation of STAT6 but not STAT4 by ConA plus IL-2-treated draining lymph node cells was increased in TMA- but not DNCB-treated mice when compared with the vehicle controls.	trimellitic anhydride	172-175	interleukin 2	Mus musculus	116-120	
12424743-8	2002	Furthermore, surface expression of B7.2 (CD86) by B cells was increased in both TMA- and DNCB-treated B6C3F1 mice when compared with the vehicles; however, greater B7.2 expression was observed in TMA-treated compared with DNCB-treated.	trimellitic anhydride	80-83	CD86 antigen	Mus musculus	35-39	
12424743-8	2002	Furthermore, surface expression of B7.2 (CD86) by B cells was increased in both TMA- and DNCB-treated B6C3F1 mice when compared with the vehicles; however, greater B7.2 expression was observed in TMA-treated compared with DNCB-treated.	trimellitic anhydride	80-83	CD86 antigen	Mus musculus	41-45	
12424743-8	2002	Furthermore, surface expression of B7.2 (CD86) by B cells was increased in both TMA- and DNCB-treated B6C3F1 mice when compared with the vehicles; however, greater B7.2 expression was observed in TMA-treated compared with DNCB-treated.	trimellitic anhydride	80-83	CD86 antigen	Mus musculus	164-168	
12424743-8	2002	Furthermore, surface expression of B7.2 (CD86) by B cells was increased in both TMA- and DNCB-treated B6C3F1 mice when compared with the vehicles; however, greater B7.2 expression was observed in TMA-treated compared with DNCB-treated.	Dinitrochlorobenzene	89-93	CD86 antigen	Mus musculus	35-39	
12424743-8	2002	Furthermore, surface expression of B7.2 (CD86) by B cells was increased in both TMA- and DNCB-treated B6C3F1 mice when compared with the vehicles; however, greater B7.2 expression was observed in TMA-treated compared with DNCB-treated.	Dinitrochlorobenzene	89-93	CD86 antigen	Mus musculus	41-45	
12424743-8	2002	Furthermore, surface expression of B7.2 (CD86) by B cells was increased in both TMA- and DNCB-treated B6C3F1 mice when compared with the vehicles; however, greater B7.2 expression was observed in TMA-treated compared with DNCB-treated.	Dinitrochlorobenzene	89-93	CD86 antigen	Mus musculus	164-168	
12424743-8	2002	Furthermore, surface expression of B7.2 (CD86) by B cells was increased in both TMA- and DNCB-treated B6C3F1 mice when compared with the vehicles; however, greater B7.2 expression was observed in TMA-treated compared with DNCB-treated.	trimellitic anhydride	196-199	CD86 antigen	Mus musculus	35-39	
12424743-8	2002	Furthermore, surface expression of B7.2 (CD86) by B cells was increased in both TMA- and DNCB-treated B6C3F1 mice when compared with the vehicles; however, greater B7.2 expression was observed in TMA-treated compared with DNCB-treated.	trimellitic anhydride	196-199	CD86 antigen	Mus musculus	41-45	
12424743-8	2002	Furthermore, surface expression of B7.2 (CD86) by B cells was increased in both TMA- and DNCB-treated B6C3F1 mice when compared with the vehicles; however, greater B7.2 expression was observed in TMA-treated compared with DNCB-treated.	trimellitic anhydride	196-199	CD86 antigen	Mus musculus	164-168	
12424743-8	2002	Furthermore, surface expression of B7.2 (CD86) by B cells was increased in both TMA- and DNCB-treated B6C3F1 mice when compared with the vehicles; however, greater B7.2 expression was observed in TMA-treated compared with DNCB-treated.	Dinitrochlorobenzene	222-226	CD86 antigen	Mus musculus	35-39	
12424743-8	2002	Furthermore, surface expression of B7.2 (CD86) by B cells was increased in both TMA- and DNCB-treated B6C3F1 mice when compared with the vehicles; however, greater B7.2 expression was observed in TMA-treated compared with DNCB-treated.	Dinitrochlorobenzene	222-226	CD86 antigen	Mus musculus	41-45	
12424743-10	2002	Furthermore, differential activation of STAT6 and expression of CD86 following exposure to TMA and DNCB may contribute to the differential production of IgE and cytokines.	trimellitic anhydride	91-94	signal transducer and activator of transcription 6	Mus musculus	40-45	
12424743-10	2002	Furthermore, differential activation of STAT6 and expression of CD86 following exposure to TMA and DNCB may contribute to the differential production of IgE and cytokines.	trimellitic anhydride	91-94	CD86 antigen	Mus musculus	64-68	
12424743-10	2002	Furthermore, differential activation of STAT6 and expression of CD86 following exposure to TMA and DNCB may contribute to the differential production of IgE and cytokines.	Dinitrochlorobenzene	99-103	signal transducer and activator of transcription 6	Mus musculus	40-45	
12424743-10	2002	Furthermore, differential activation of STAT6 and expression of CD86 following exposure to TMA and DNCB may contribute to the differential production of IgE and cytokines.	Dinitrochlorobenzene	99-103	CD86 antigen	Mus musculus	64-68