PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12393358-3 2002 Our aim was to establish if measurements of halothane-induced increases in intracellular calcium ion concentration [Ca(2+)](i) in cultured human skeletal muscle cells can be used to phenotype MH susceptibility and if different mutations in the ryanodine receptor (RYR1) gene affect halothane-induced increases in [Ca(2+)](i). Halothane 44-53 ryanodine receptor 1 Homo sapiens 264-268