PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12390318-0 2002 Ribavirin increases mitogen- and antigen-induced expression of CD40L on CD4+ T cells in vivo. Ribavirin 0-9 CD4 molecule Homo sapiens 63-66 12390318-3 2002 In contrast, after stimulation with both HCV core antigen and phorbol myristate acetate (PMA) plus ionomycin (IO), the expression of CD40L on CD4 lymphocytes was significantly higher in the ribavirin group compared with controls. Ribavirin 190-199 CD4 molecule Homo sapiens 133-136 12390318-6 2002 In conclusion, these data indicate that ribavirin -upmodulates CD40L expression on CD4 T cells, a property which may account in part for its ability to enhance the antiviral activity of interferon-alpha in the treatment of chronic HCV infection. Ribavirin 40-49 CD4 molecule Homo sapiens 63-66