PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12351406-0	2002	SU5416 and SU5614 inhibit kinase activity of wild-type and mutant FLT3 receptor tyrosine kinase.	SU 5614	11-17	fms related receptor tyrosine kinase 3	Homo sapiens	66-70	
12351406-6	2002	Both SU5416 and SU5614 were capable of inhibiting autophosphorylation of ITD and WT FLT3 (SU5416 concentration that inhibits 50% [IC(50)], 100 nM; and SU5614 IC(50) 10 nM).	SU 5614	16-22	fms related receptor tyrosine kinase 3	Homo sapiens	84-88	
12351406-8	2002	FLT3 inhibition by SU5416 and SU5614 resulted in reduced proliferation (IC(50), 250 nM and 100 nM, respectively) and induction of apoptosis of FLT3 ITD-positive leukemic cell lines.	SU 5614	30-36	fms related receptor tyrosine kinase 3	Homo sapiens	0-4	
12351406-8	2002	FLT3 inhibition by SU5416 and SU5614 resulted in reduced proliferation (IC(50), 250 nM and 100 nM, respectively) and induction of apoptosis of FLT3 ITD-positive leukemic cell lines.	SU 5614	30-36	fms related receptor tyrosine kinase 3	Homo sapiens	143-147	
12351406-10	2002	We conclude that SU5416 and SU5614 are potent inhibitors of FLT3.	SU 5614	28-34	fms related receptor tyrosine kinase 3	Homo sapiens	60-64