PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12237339-0	2002	Identification of a mechanism by which the methylmercury antidotes N-acetylcysteine and dimercaptopropanesulfonate enhance urinary metal excretion: transport by the renal organic anion transporter-1.	Acetylcysteine	67-83	solute carrier family 22 member 6	Rattus norvegicus	165-198	
12237339-0	2002	Identification of a mechanism by which the methylmercury antidotes N-acetylcysteine and dimercaptopropanesulfonate enhance urinary metal excretion: transport by the renal organic anion transporter-1.	dimercaptopropanesulfonate	88-114	solute carrier family 22 member 6	Rattus norvegicus	165-198	
12237339-0	2002	Identification of a mechanism by which the methylmercury antidotes N-acetylcysteine and dimercaptopropanesulfonate enhance urinary metal excretion: transport by the renal organic anion transporter-1.	Metals	131-136	solute carrier family 22 member 6	Rattus norvegicus	165-198	
12237339-4	2002	Xenopus laevis oocytes expressing rat Oat1 showed increased uptake of [(14)C]MeHg when complexed with either NAC or DMPS but not when complexed with L-cysteine, glutathione, dimercaptosuccinate, penicillamine, or gamma-glutamylcysteine.	Acetylcysteine	109-112	solute carrier family 22 member 6	Rattus norvegicus	38-42	
12237339-4	2002	Xenopus laevis oocytes expressing rat Oat1 showed increased uptake of [(14)C]MeHg when complexed with either NAC or DMPS but not when complexed with L-cysteine, glutathione, dimercaptosuccinate, penicillamine, or gamma-glutamylcysteine.	Unithiol	116-120	solute carrier family 22 member 6	Rattus norvegicus	38-42	
12237339-4	2002	Xenopus laevis oocytes expressing rat Oat1 showed increased uptake of [(14)C]MeHg when complexed with either NAC or DMPS but not when complexed with L-cysteine, glutathione, dimercaptosuccinate, penicillamine, or gamma-glutamylcysteine.	dimercaptosuccinate	174-193	solute carrier family 22 member 6	Rattus norvegicus	38-42	
12237339-4	2002	Xenopus laevis oocytes expressing rat Oat1 showed increased uptake of [(14)C]MeHg when complexed with either NAC or DMPS but not when complexed with L-cysteine, glutathione, dimercaptosuccinate, penicillamine, or gamma-glutamylcysteine.	Penicillamine	195-208	solute carrier family 22 member 6	Rattus norvegicus	38-42	
12237339-4	2002	Xenopus laevis oocytes expressing rat Oat1 showed increased uptake of [(14)C]MeHg when complexed with either NAC or DMPS but not when complexed with L-cysteine, glutathione, dimercaptosuccinate, penicillamine, or gamma-glutamylcysteine.	gamma-glutamylcysteine	213-235	solute carrier family 22 member 6	Rattus norvegicus	38-42	
12237339-6	2002	The apparent K(m) values for Oat1-mediated transport were 31 +/- 2 microM for MeHg-NAC and 9 +/- 2 microM for MeHg-DMPS, indicating that these are relatively high-affinity substrates.	Acetylcysteine	83-86	solute carrier family 22 member 6	Rattus norvegicus	29-33	
12237339-6	2002	The apparent K(m) values for Oat1-mediated transport were 31 +/- 2 microM for MeHg-NAC and 9 +/- 2 microM for MeHg-DMPS, indicating that these are relatively high-affinity substrates.	mehg-dmps	110-119	solute carrier family 22 member 6	Rattus norvegicus	29-33	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	Carbon-14	24-30	solute carrier family 22 member 6	Rattus norvegicus	0-4	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	Carbon-14	24-30	solute carrier family 22 member 6	Rattus norvegicus	106-110	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	mehg	31-35	solute carrier family 22 member 6	Rattus norvegicus	0-4	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	mehg	31-35	solute carrier family 22 member 6	Rattus norvegicus	106-110	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	Acetylcysteine	36-39	solute carrier family 22 member 6	Rattus norvegicus	0-4	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	Acetylcysteine	36-39	solute carrier family 22 member 6	Rattus norvegicus	106-110	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	Carbon-14	44-50	solute carrier family 22 member 6	Rattus norvegicus	0-4	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	Carbon-14	44-50	solute carrier family 22 member 6	Rattus norvegicus	106-110	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	mehg	51-55	solute carrier family 22 member 6	Rattus norvegicus	0-4	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	mehg	51-55	solute carrier family 22 member 6	Rattus norvegicus	106-110	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	Unithiol	56-60	solute carrier family 22 member 6	Rattus norvegicus	0-4	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	Unithiol	56-60	solute carrier family 22 member 6	Rattus norvegicus	106-110	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	p-Aminohippuric Acid	122-138	solute carrier family 22 member 6	Rattus norvegicus	0-4	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	p-Aminohippuric Acid	122-138	solute carrier family 22 member 6	Rattus norvegicus	106-110	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	p-Aminohippuric Acid	140-143	solute carrier family 22 member 6	Rattus norvegicus	0-4	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	p-Aminohippuric Acid	140-143	solute carrier family 22 member 6	Rattus norvegicus	106-110	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	Glutarates	209-218	solute carrier family 22 member 6	Rattus norvegicus	0-4	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	Glutarates	209-218	solute carrier family 22 member 6	Rattus norvegicus	106-110	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	Glutamic Acid	227-236	solute carrier family 22 member 6	Rattus norvegicus	0-4	
12237339-7	2002	Oat1-mediated uptake of [(14)C]MeHg-NAC and [(14)C]MeHg-DMPS was inhibited by prototypical substrates for Oat1, including p-aminohippurate (PAH), and was trans-stimulated when oocytes were preloaded with 2 mM glutarate but not glutamate.	Glutamic Acid	227-236	solute carrier family 22 member 6	Rattus norvegicus	106-110	
12237339-8	2002	Conversely, efflux of [(3)H]PAH from Oat1-expressing oocytes was trans-stimulated by glutarate, PAH, NAC, DMPS, MeHg-NAC, MeHg-DMPS, and a mercapturic acid, indicating that these are transported solutes.	Tritium	22-27	solute carrier family 22 member 6	Rattus norvegicus	37-41	
12237339-8	2002	Conversely, efflux of [(3)H]PAH from Oat1-expressing oocytes was trans-stimulated by glutarate, PAH, NAC, DMPS, MeHg-NAC, MeHg-DMPS, and a mercapturic acid, indicating that these are transported solutes.	p-Aminohippuric Acid	28-31	solute carrier family 22 member 6	Rattus norvegicus	37-41	
12237339-8	2002	Conversely, efflux of [(3)H]PAH from Oat1-expressing oocytes was trans-stimulated by glutarate, PAH, NAC, DMPS, MeHg-NAC, MeHg-DMPS, and a mercapturic acid, indicating that these are transported solutes.	Glutarates	85-94	solute carrier family 22 member 6	Rattus norvegicus	37-41	
12237339-8	2002	Conversely, efflux of [(3)H]PAH from Oat1-expressing oocytes was trans-stimulated by glutarate, PAH, NAC, DMPS, MeHg-NAC, MeHg-DMPS, and a mercapturic acid, indicating that these are transported solutes.	p-Aminohippuric Acid	96-99	solute carrier family 22 member 6	Rattus norvegicus	37-41	
12237339-8	2002	Conversely, efflux of [(3)H]PAH from Oat1-expressing oocytes was trans-stimulated by glutarate, PAH, NAC, DMPS, MeHg-NAC, MeHg-DMPS, and a mercapturic acid, indicating that these are transported solutes.	Acetylcysteine	101-104	solute carrier family 22 member 6	Rattus norvegicus	37-41	
12237339-8	2002	Conversely, efflux of [(3)H]PAH from Oat1-expressing oocytes was trans-stimulated by glutarate, PAH, NAC, DMPS, MeHg-NAC, MeHg-DMPS, and a mercapturic acid, indicating that these are transported solutes.	Unithiol	106-110	solute carrier family 22 member 6	Rattus norvegicus	37-41	
12237339-8	2002	Conversely, efflux of [(3)H]PAH from Oat1-expressing oocytes was trans-stimulated by glutarate, PAH, NAC, DMPS, MeHg-NAC, MeHg-DMPS, and a mercapturic acid, indicating that these are transported solutes.	Acetylcysteine	117-120	solute carrier family 22 member 6	Rattus norvegicus	37-41	
12237339-8	2002	Conversely, efflux of [(3)H]PAH from Oat1-expressing oocytes was trans-stimulated by glutarate, PAH, NAC, DMPS, MeHg-NAC, MeHg-DMPS, and a mercapturic acid, indicating that these are transported solutes.	mehg-dmps	122-131	solute carrier family 22 member 6	Rattus norvegicus	37-41	
12237339-8	2002	Conversely, efflux of [(3)H]PAH from Oat1-expressing oocytes was trans-stimulated by glutarate, PAH, NAC, DMPS, MeHg-NAC, MeHg-DMPS, and a mercapturic acid, indicating that these are transported solutes.	Acetylcysteine	139-155	solute carrier family 22 member 6	Rattus norvegicus	37-41	
12237339-9	2002	[(3)H]PAH uptake was competitively inhibited by NAC (K(i) of 2.0 +/- 0.3 mM) and DMPS (K(i) of 0.10 +/- 0.02 mM), providing further evidence that these chelating agents are substrates for Oat1.	p-Aminohippuric Acid	6-9	solute carrier family 22 member 6	Rattus norvegicus	188-192	
12237339-9	2002	[(3)H]PAH uptake was competitively inhibited by NAC (K(i) of 2.0 +/- 0.3 mM) and DMPS (K(i) of 0.10 +/- 0.02 mM), providing further evidence that these chelating agents are substrates for Oat1.	Acetylcysteine	48-51	solute carrier family 22 member 6	Rattus norvegicus	188-192	
12237339-10	2002	These results indicate that the MeHg antidotes NAC and DMPS and their mercaptide complexes are transported by Oat1 but are comparatively poor substrates for Oat3.	Acetylcysteine	47-50	solute carrier family 22 member 6	Rattus norvegicus	110-114	
12237339-10	2002	These results indicate that the MeHg antidotes NAC and DMPS and their mercaptide complexes are transported by Oat1 but are comparatively poor substrates for Oat3.	Acetylcysteine	47-50	solute carrier family 22 member 8	Rattus norvegicus	157-161	
12237339-10	2002	These results indicate that the MeHg antidotes NAC and DMPS and their mercaptide complexes are transported by Oat1 but are comparatively poor substrates for Oat3.	Unithiol	55-59	solute carrier family 22 member 6	Rattus norvegicus	110-114	
12237339-10	2002	These results indicate that the MeHg antidotes NAC and DMPS and their mercaptide complexes are transported by Oat1 but are comparatively poor substrates for Oat3.	Unithiol	55-59	solute carrier family 22 member 8	Rattus norvegicus	157-161	
12237339-10	2002	These results indicate that the MeHg antidotes NAC and DMPS and their mercaptide complexes are transported by Oat1 but are comparatively poor substrates for Oat3.	mercaptide	70-80	solute carrier family 22 member 6	Rattus norvegicus	110-114	
12237339-10	2002	These results indicate that the MeHg antidotes NAC and DMPS and their mercaptide complexes are transported by Oat1 but are comparatively poor substrates for Oat3.	mercaptide	70-80	solute carrier family 22 member 8	Rattus norvegicus	157-161