PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12171915-0	2002	Phenylethyl isothiocyanate induces apoptotic signaling via suppressing phosphatase activity against c-Jun N-terminal kinase.	phenethyl isothiocyanate	0-26	mitogen-activated protein kinase 8	Homo sapiens	100-123	
12171915-2	2002	We found that phenylethyl isothiocyanate (PEITC) was capable of inducing JNK activation and apoptosis in prostate cancer cell lines with distinct p53 statuses.	phenethyl isothiocyanate	14-40	mitogen-activated protein kinase 8	Homo sapiens	73-76	
12171915-2	2002	We found that phenylethyl isothiocyanate (PEITC) was capable of inducing JNK activation and apoptosis in prostate cancer cell lines with distinct p53 statuses.	phenethyl isothiocyanate	42-47	mitogen-activated protein kinase 8	Homo sapiens	73-76	
12171915-3	2002	PEITC induced JNK-mediated apoptotic signaling via a different pathway than that used by DNA-damaging agents, because genotoxicresistant LNCaP prostate cancer cells were equally sensitive to PEITC as parental LNCaP cells.	phenethyl isothiocyanate	0-5	mitogen-activated protein kinase 8	Homo sapiens	14-17	
12171915-5	2002	The JNK dephosphorylation and inactivation rates were decreased in cells exposed to PEITC.	phenethyl isothiocyanate	84-89	mitogen-activated protein kinase 8	Homo sapiens	4-7	
12171915-7	2002	Taken together, our data suggest that PEITC activates JNK through suppression of JNK dephosphorylation and that PEITC may be an alternative therapeutic agent for cancers that are resistant to genotoxic agents.	phenethyl isothiocyanate	38-43	mitogen-activated protein kinase 8	Homo sapiens	54-57	
12171915-7	2002	Taken together, our data suggest that PEITC activates JNK through suppression of JNK dephosphorylation and that PEITC may be an alternative therapeutic agent for cancers that are resistant to genotoxic agents.	phenethyl isothiocyanate	38-43	mitogen-activated protein kinase 8	Homo sapiens	81-84