PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12114539-0	2002	mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.	gadd	117-121	interleukin 24	Homo sapiens	0-5	
12114539-0	2002	mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.	gadd	117-121	interleukin 24	Homo sapiens	7-12	
12114539-5	2002	Infection of melanoma cells, but not normal immortal melanocytes, with Ad.mda-7 induced a time- and dose-dependent increase in expression, mRNA and protein, of a family of growth arrest and DNA damage (GADD)-inducible genes, which correlated with induction of apoptosis.	gadd	202-206	interleukin 24	Homo sapiens	74-79	
12114539-10	2002	In addition, SB203580 effectively inhibited Ad.mda-7-mediated induction of the GADD family of genes in a time- and dose-dependent manner, and it effectively blocked Ad.mda-7-mediated down-regulation of the antiapoptotic protein BCL-2.	gadd	79-83	interleukin 24	Homo sapiens	47-52	
12114539-10	2002	In addition, SB203580 effectively inhibited Ad.mda-7-mediated induction of the GADD family of genes in a time- and dose-dependent manner, and it effectively blocked Ad.mda-7-mediated down-regulation of the antiapoptotic protein BCL-2.	gadd	79-83	interleukin 24	Homo sapiens	168-173	
12114539-11	2002	Inhibition of GADD genes by an antisense approach either alone or in combination also effectively blocked Ad.mda-7-induced apoptosis in melanoma cells.	gadd	14-18	interleukin 24	Homo sapiens	109-114	
12114539-12	2002	These results support the hypothesis that Ad.mda-7 mediates induction of the GADD family of genes by means of the p38 MAPK pathway, thereby resulting in the selective induction of apoptosis in human melanoma cells.	gadd	77-81	interleukin 24	Homo sapiens	45-50