PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12020745-0 2002 Effects of testosterone and 17-beta-estradiol on TNF-alpha-induced E-selectin and VCAM-1 expression in endothelial cells. Testosterone 11-23 vascular cell adhesion molecule 1 Homo sapiens 82-88 12020745-4 2002 As shown by Western blot analysis, co-administration with testosterone or 17-beta-estradiol increased the expression of E-selectin and VCAM-1 induced by TNF-alpha at 6 h and 3 h, respectively. Testosterone 58-70 vascular cell adhesion molecule 1 Homo sapiens 135-141 12020745-5 2002 Similarly, RT-PCR analysis revealed a significant increase in the amount of mRNA for E-selectin and VCAM-1 after co-administration with testosterone or 17-beta-estradiol in TNF-alpha-stimulated HUVEC. Testosterone 136-148 vascular cell adhesion molecule 1 Homo sapiens 100-106 12020745-7 2002 Flow cytometric analysis showed that preincubation with androgen receptor antagonist cyproterone and estrogen receptor antagonist tamoxifen completely abrogated the upregulating effects of testosterone and 17-beta-estradiol on TNF-alpha-induced E-selectin and VCAM-1 expression, respectively. Testosterone 189-201 vascular cell adhesion molecule 1 Homo sapiens 260-266 12020745-9 2002 The data indicate that both testosterone and 17-beta-estradiol increase TNF-alpha-induced E-selectin and VCAM-1 expression in endothelial cells via a receptor-mediated system, and expression of TNF receptors are not changed in these actions. Testosterone 28-40 vascular cell adhesion molecule 1 Homo sapiens 105-111