PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11956159-5	2002	Further, both okadaic acid and peroxyvanadate attenuate cAMP-stimulated increases in endogenous hCYP17 mRNA expression and in hCYP17 promoter-reporter construct luciferase activity.	Cyclic AMP	56-60	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	96-102	
11956159-0	2002	Adrenocorticotropin/cyclic adenosine 3",5"-monophosphate-mediated transcription of the human CYP17 gene in the adrenal cortex is dependent on phosphatase activity.	Cyclic AMP	20-56	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	93-98	
11956159-4	2002	Using inhibitors of serine/threonine phosphatase activity (okadaic acid) and phosphotyrosine phosphatase activity (peroxyvanadate), we can inhibit the cAMP-inducible binding of the steroidogenic factor-1 (SF-1), p54(nrb)/NonO, and polypyrimidine tract-binding protein-associated splicing factor (PSF) complex required for regulation of transcription to the promoter of hCYP17.	Cyclic AMP	151-155	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	369-375	
11956159-5	2002	Further, both okadaic acid and peroxyvanadate attenuate cAMP-stimulated increases in endogenous hCYP17 mRNA expression and in hCYP17 promoter-reporter construct luciferase activity.	Cyclic AMP	56-60	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	126-132	
11956159-7	2002	Our findings demonstrate that activation of protein phosphatase(s) is essential for cAMP-dependent transcription of hCYP17 in H295R cells and suggest a role for PKA in phosphatase activation, which leads to dephosphorylation of SF-1 and increased gene transcription.	Cyclic AMP	84-88	cytochrome P450 family 17 subfamily A member 1	Homo sapiens	116-122